Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 7/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MIF | P14174 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22469513 | 0.81 | GRIN2D (0.37) | CYP3A4ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL29800259 | 0.81 | GRIN2D (0.37) | CYP3A4ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL1809938 | 0.79 | ERN1 (0.36) | ERN1CYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL23361148 | 0.77 | ERN1 (0.51) | ERN1HPGDALDH1A1TDP1 | |
| SCHEMBL23361002 | 0.75 | WDR5 (0.32) | — | |
| SCHEMBL29945096 | 0.74 | DRD1 (0.32) | ERN1HSD17B10 | |
| SCHEMBL28863821 | 0.74 | DRD1 (0.32) | ERN1HSD17B10 | |
| SCHEMBL11179328 | 0.73 | ERN1 (0.43) | ERN1HPGDTSHRHSD17B10CYP3A4 | |
| SCHEMBL1459005 | 0.73 | HSD17B10 (0.41) | ERN1HPGDHSD17B10CYP3A4ALDH1A1 | |
| SCHEMBL11712559 | 0.73 | HSD17B10 (0.40) | HPGDTSHRHSD17B10CYP3A4HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112812113-B | Immunomodulatory compounds, compositions and uses thereof | 杭州和正医药有限公司 | 2022-09-20 | — | — | CN | disclosed |