Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 9/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | TSPO | P30536 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL633639 | 0.86 | HPGD (0.39) | MRGPRX4HPGDKMT2AMEN1MAPT | |
| SCHEMBL2422410 | 0.83 | FOLH1 (0.53) | HMGB1HPGDKMT2AMAPTFOLH1 | |
| SCHEMBL4968519 | 0.82 | ALDH1A1 (0.47) | MRGPRX4KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL2833475 | 0.81 | MRGPRX4 (0.43) | MRGPRX4ALBHMGB1HPGDFOLH1 | |
| SCHEMBL1245939 | 0.81 | TSHR (0.52) | MRGPRX4HMGB1HPGDKMT2AFOLH1 | |
| SCHEMBL31384443 | 0.81 | HMGB1 (0.40) | MRGPRX4HMGB1HPGDKMT2AMAPT | |
| SCHEMBL31384413 | 0.81 | MRGPRX4 (0.51) | MRGPRX4HMGB1HPGDKMT2AFOLH1 | |
| SCHEMBL205733 | 0.81 | MRGPRX4 (0.45) | MRGPRX4HMGB1HPGDKMT2AMEN1 | |
| SCHEMBL1401459 | 0.79 | MRGPRX4 (0.49) | MRGPRX4ALBHMGB1HPGDFOLH1 | |
| SCHEMBL4238088 | 0.79 | KAT6A (0.54) | MRGPRX4ALBHMGB1HPGDFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106573915-A | Compounds active against bromodomains | 纽韦卢森公司 | 2017-04-19 | — | — | CN | disclosed |