SCHEMBL28844089

SCHEMBL28844089

CC1=CCC(C)(NC(=O)O)C=C1

nearest known ligand 0.39

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22849723 0.84 HSD11B1 (0.34) HSD11B1
SCHEMBL2470442 0.73 HSD11B1 (0.41) HSD11B1
SCHEMBL6282920 0.72
SCHEMBL1647978 0.70 HSD11B1 (0.36) HSD11B1
SCHEMBL20420817 0.69 HSD11B1 (0.41) HSD11B1
SCHEMBL25336093 0.69 HSD11B1 (0.38) HSD11B1
SCHEMBL29502628 0.68 HSD11B1 (0.37) HSD11B1
SCHEMBL28980668 0.68 HSD11B1 (0.40) HSD11B1
SCHEMBL11543971 0.68 HSD11B1 (0.40) HSD11B1
SCHEMBL19042880 0.68 HSD11B1 (0.37) HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114929672-A Cancer therapy targeting cancer stem cells 治疗方案股份有限公司 2022-08-19 CN disclosed