Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 6/20 | 0.65 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.56 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.56 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.56 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.54 |
| ▸ | PPARG | P37231 | 6/20 | 0.54 |
| ▸ | PPARD | Q03181 | 6/20 | 0.54 |
| ▸ | PPARA | Q07869 | 6/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TLR2 | O60603 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | FABP4 | P15090 | 2/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.54 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.54 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28282505 | 1.00 | FOLH1 (0.65) | FOLH1FFAR4FFAR1GRIK1GRIK2 | |
| SCHEMBL27971038 | 1.00 | FOLH1 (0.65) | FOLH1FFAR4FFAR1GRIK1GRIK2 | |
| SCHEMBL27959752 | 1.00 | FOLH1 (0.65) | FOLH1FFAR4FFAR1GRIK1GRIK2 | |
| SCHEMBL27971196 | 1.00 | FOLH1 (0.65) | FOLH1FFAR4FFAR1GRIK1GRIK2 | |
| SCHEMBL28813006 | 1.00 | FOLH1 (0.65) | FOLH1FFAR4FFAR1GRIK1GRIK2 | |
| SCHEMBL28274788 | 1.00 | FOLH1 (0.65) | FOLH1FFAR4FFAR1GRIK1GRIK2 | |
| SCHEMBL1506893 | 0.98 | FOLH1 (0.67) | FOLH1FFAR4FFAR1GRIK1GRIK2 | |
| SCHEMBL3619652 | 0.98 | FOLH1 (0.67) | FOLH1FFAR4FFAR1GRIK1GRIK2 | |
| SCHEMBL1134819 | 0.98 | FOLH1 (0.67) | FOLH1FFAR4FFAR1GRIK1GRIK2 | |
| SCHEMBL1506898 | 0.98 | FOLH1 (0.67) | FOLH1FFAR4FFAR1GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106660943-A | Metal/radiometal labeled PSMA inhibitors for PSMA-targeted imaging and radiotherapy | 约翰霍普金斯大学 | 2017-05-10 | — | — | CN | disclosed |