Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 5/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | HNF4A | P41235 | 1/20 | 0.39 |
| ▸ | ICMT | O60725 | 1/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17331691 | 0.82 | KDM4E (0.55) | KDM4EALDH1A1MAPTSMN1; SMN2HTT | |
| SCHEMBL17331720 | 0.77 | DHODH (0.38) | DHODHPTGER1KDM4ENPC1ALDH1A1 | |
| SCHEMBL17331406 | 0.74 | TAAR1 (0.43) | DHODHKDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL269851 | 0.71 | HTT (0.59) | DCLRE1BDHODHNR4A1NR4A2NR4A3 | |
| SCHEMBL31397801 | 0.71 | HTT (0.59) | DCLRE1BDHODHNR4A1NR4A2NR4A3 | |
| SCHEMBL28146473 | 0.71 | ALDH1A1 (0.44) | DHODHKDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL27836738 | 0.71 | KDM4E (0.58) | DHODHKDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL28145385 | 0.70 | ALDH1A1 (0.46) | DHODHNR4A1KDM4ENPC1ALDH1A1 | |
| SCHEMBL2807005 | 0.70 | ALDH1A1 (0.56) | DHODHKDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL28145413 | 0.69 | TRPV1 (0.47) | DCLRE1BDHODHNR4A1NR4A2NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106661019-A | Indolizine derivatives as phoshoinositide 3-kinases inhibitors | 奇斯药制品公司 | 2017-05-10 | — | — | CN | disclosed |