Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | BIRC2 | Q13490 | 5/20 | 0.43 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23834150 | 0.98 | CA2 (0.54) | CA2CA1ZDHHC7TSHRBIRC2 | |
| SCHEMBL28844464 | 0.98 | CA2 (0.54) | CA2CA1ZDHHC7TSHRBIRC2 | |
| SCHEMBL11340947 | 0.95 | CA2 (0.54) | CA2CA1ZDHHC7TSHRBIRC2 | |
| SCHEMBL11335675 | 0.95 | CA2 (0.54) | CA2CA1ZDHHC7TSHRBIRC2 | |
| SCHEMBL11341296 | 0.95 | CA2 (0.54) | CA2CA1ZDHHC7TSHRBIRC2 | |
| SCHEMBL11331602 | 0.95 | CA2 (0.62) | CA2CA1ZDHHC7TSHRBIRC2 | |
| SCHEMBL3115757 | 0.93 | CA2 (0.61) | CA2CA1ZDHHC7TSHRBIRC2 | |
| SCHEMBL3120264 | 0.92 | CA2 (0.59) | CA2CA1ZDHHC7TSHRBIRC2 | |
| SCHEMBL3120056 | 0.92 | CA2 (0.59) | CA2CA1ZDHHC7TSHRBIRC2 | |
| SCHEMBL3117186 | 0.92 | CA2 (0.59) | CA2CA1ZDHHC7TSHRBIRC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112533929-B | Indole macrocyclic derivatives, preparation method and medical application thereof | 福建盛迪医药有限公司 | 2022-09-16 | — | — | CN | disclosed |