Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.51 |
| ▸ | TDO2 | P48775 | 2/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.50 |
| ▸ | TUBB | P07437 | 4/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.50 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.50 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.50 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.50 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.50 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.50 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.50 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.50 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.50 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.50 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.50 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.50 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | CDC25B | P30305 | 3/20 | 0.47 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28463961 | 0.90 | IDO1 (0.55) | IDO1TDO2TUBB4ATUBBTUBA3C | |
| SCHEMBL28844635 | 0.86 | IDO1 (0.57) | IDO1TDO2TUBB4ATUBBTUBA3C | |
| SCHEMBL28168843 | 0.85 | IDO1 (0.67) | IDO1TDO2TUBB4ATUBBTUBA3C | |
| SCHEMBL28460071 | 0.84 | IDO1 (0.55) | IDO1TDO2TUBB4ATUBBTUBA3C | |
| SCHEMBL28844747 | 0.84 | IDO1 (0.55) | IDO1TDO2TUBB4ATUBBTUBA3C | |
| SCHEMBL28461243 | 0.84 | FBP1 (0.62) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL28844693 | 0.82 | IDO1 (0.76) | IDO1TDO2 | |
| SCHEMBL699482 | 0.80 | FLT3 (0.60) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28464886 | 0.78 | FBP1 (0.65) | IDO1TDO2FBP1 | |
| SCHEMBL29865229 | 0.77 | IDO1 (0.58) | IDO1TDO2CDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483366-B | Indole compound and preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2022-09-16 | — | — | CN | disclosed |