Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 13/20 | 0.54 |
| ▸ | TDO2 | P48775 | 13/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | FBP1 | P09467 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28953327 | 0.87 | IDO1 (0.70) | IDO1TDO2FBP1 | |
| SCHEMBL29865025 | 0.87 | IDO1 (0.70) | IDO1TDO2FBP1 | |
| SCHEMBL28467705 | 0.84 | IDO1 (0.76) | IDO1TDO2ALDH1A1MMP13 | |
| SCHEMBL28844632 | 0.84 | IDO1 (0.58) | IDO1TDO2ALDH1A1FBP1MMP13 | |
| SCHEMBL29865059 | 0.84 | IDO1 (0.58) | IDO1TDO2ALDH1A1FBP1MMP13 | |
| SCHEMBL29865145 | 0.84 | IDO1 (0.76) | IDO1TDO2ALDH1A1MMP13 | |
| SCHEMBL29865182 | 0.81 | TDO2 (0.57) | IDO1TDO2 | |
| SCHEMBL28953333 | 0.81 | TDO2 (0.57) | IDO1TDO2 | |
| SCHEMBL28463699 | 0.77 | IDO1 (0.64) | IDO1TDO2FBP1MMP13 | |
| SCHEMBL29865146 | 0.77 | IDO1 (0.64) | IDO1TDO2FBP1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483366-B | Indole compound and preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2022-09-16 | — | — | CN | disclosed |