Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.64 |
| ▸ | MEN1 | O00255 | 7/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.63 |
| ▸ | MAPT | P10636 | 6/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.50 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28844657 | 0.88 | KMT2A (0.63) | PDE7AKMT2AMEN1GAAPKM | |
| SCHEMBL29130743 | 0.86 | HGFAC (0.62) | PDE7AKMT2AMEN1GAAPKM | |
| SCHEMBL9367473 | 0.83 | PDE7A (0.74) | PDE7AKMT2AMEN1GAAPKM | |
| SCHEMBL11760667 | 0.83 | PDE7A (1.00) | PDE7AKMT2AMEN1GAAPKM | |
| SCHEMBL2967458 | 0.83 | PDE7A (0.78) | PDE7AKMT2AMEN1GAAPKM | |
| SCHEMBL3509441 | 0.82 | PDE7A (0.68) | PDE7AKMT2AMEN1GAAPKM | |
| SCHEMBL29251429 | 0.82 | PDE7A (0.54) | PDE7AKMT2AMEN1GAAPKM | |
| SCHEMBL11198374 | 0.81 | PDE7A (0.76) | PDE7AKMT2AMEN1GAAPKM | |
| SCHEMBL22069562 | 0.80 | PDE7A (0.74) | PDE7AKMT2AMEN1GAAPKM | |
| SCHEMBL4029870 | 0.80 | PDE7A (0.73) | PDE7AKMT2AMEN1GAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483366-B | Indole compound and preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2022-09-16 | — | — | CN | disclosed |