Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.63 |
| ▸ | MEN1 | O00255 | 7/20 | 0.63 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28844690 | 0.88 | PDE7A (0.71) | KMT2AMEN1PDE7AALDH1A1GPR55 | |
| SCHEMBL23174950 | 0.85 | MEN1 (0.50) | KMT2AMEN1PDE7AALDH1A1GPR55 | |
| SCHEMBL3506576 | 0.83 | PDE7A (0.66) | KMT2AMEN1PDE7AALDH1A1GPR55 | |
| SCHEMBL29130743 | 0.82 | HGFAC (0.62) | KMT2AMEN1PDE7AALDH1A1MAPT | |
| SCHEMBL3507438 | 0.82 | MEN1 (0.65) | KMT2AMEN1PDE7AALDH1A1GPR55 | |
| SCHEMBL4790993 | 0.82 | MAPT (0.71) | KMT2AMEN1PDE7AALDH1A1GPR55 | |
| SCHEMBL8810667 | 0.82 | PDE7A (0.72) | KMT2AMEN1PDE7AALDH1A1GPR55 | |
| SCHEMBL2529627 | 0.81 | ALDH1A1 (0.67) | KMT2AMEN1PDE7AALDH1A1GPR55 | |
| SCHEMBL29251429 | 0.81 | PDE7A (0.54) | KMT2AMEN1PDE7AALDH1A1GPR55 | |
| SCHEMBL3505195 | 0.81 | ALDH1A1 (0.69) | KMT2AMEN1PDE7AALDH1A1GPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483366-B | Indole compound and preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2022-09-16 | — | — | CN | disclosed |