Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.57 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | MLNR | O43193 | 1/20 | 0.57 |
| ▸ | MMP1 | P03956 | 1/20 | 0.57 |
| ▸ | MPO | P05164 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4082910 | 0.87 | HSPB1 (0.68) | MAPTLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10337156 | 0.82 | HTT (0.60) | MAPTLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11315551 | 0.82 | MEN1 (0.58) | MAPTLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3845000 | 0.82 | MAPT (0.58) | MAPTLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11874519 | 0.81 | MAPT (0.60) | MAPTLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4058420 | 0.81 | MAPT (0.60) | MAPTLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15391420 | 0.81 | CYP19A1 (0.57) | MAPTLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13860335 | 0.81 | HSPB1 (0.77) | MAPTMEN1KMT2AHIF1AMAPK1 | |
| SCHEMBL11470258 | 0.81 | MAPT (0.57) | MAPTLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1283884 | 0.80 | HSPB1 (0.71) | MAPTLMNAMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483366-B | Indole compound and preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2022-09-16 | — | — | CN | disclosed |