SCHEMBL28844746

SCHEMBL28844746

COc1cc(Nc2cc(Cl)cc3[nH]c(C(=O)O)cc23)ccc1F

nearest known ligand 0.76

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 20/20 0.76
TDO2 P48775 20/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29864939 0.87 IDO1 (0.59) IDO1TDO2
SCHEMBL29865088 0.86 IDO1 (1.00) IDO1TDO2
SCHEMBL28844568 0.86 IDO1 (1.00) IDO1TDO2
SCHEMBL28461324 0.85 IDO1 (0.72) IDO1TDO2
SCHEMBL28461153 0.85 IDO1 (0.81) IDO1TDO2
SCHEMBL29865262 0.85 IDO1 (0.81) IDO1TDO2
SCHEMBL28844620 0.82 IDO1 (0.75) IDO1TDO2
SCHEMBL28464845 0.81 FBP1 (0.69) IDO1TDO2
SCHEMBL28844775 0.81 IDO1 (1.00) IDO1TDO2
SCHEMBL29865081 0.81 IDO1 (1.00) IDO1TDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110483366-B Indole compound and preparation method, pharmaceutical composition and application thereof 中国医学科学院药物研究所 2022-09-16 CN disclosed