SCHEMBL2884482

SCHEMBL2884482

Oc1c(-c2ccccc2)cc(C2(c3cc(-c4ccccc4)c(O)c(-c4ccccc4)c3)c3ccccc3-c3ccccc32)cc1-c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 2/20 0.49
ESR1 P03372 1/20 0.49
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
KDM4E B2RXH2 1/20 0.44
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.44
OPRK1 P41145 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
BACE1 P56817 2/20 0.43
ALDH1A1 P00352 1/20 0.42
HPGD P15428 1/20 0.42
BCL2L1 Q07817 1/20 0.42
HSD17B10 Q99714 1/20 0.42
THRB P10828 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32677798 1.00 ESR2 (0.49) ESR2ESR1MEN1KMT2AKDM4E
SCHEMBL22829524 0.91 ESR1 (0.49) ESR2ESR1MEN1KMT2AKDM4E
SCHEMBL14198946 0.89 HSP90AA1 (0.46) ESR2ESR1MEN1KMT2AKDM4E
SCHEMBL25636435 0.87 ESR1 (0.42) ESR2ESR1MEN1KMT2AKDM4E
SCHEMBL20752931 0.83 PTPN1 (0.43) ESR2ESR1BCL2L1PTPN1PDK2
SCHEMBL218750 0.82 ESR1 (0.63) ESR2ESR1MEN1KMT2AKDM4E
SCHEMBL29389637 0.82 ESR1 (0.63) ESR2ESR1MEN1KMT2AKDM4E
SCHEMBL29837106 0.82 ESR1 (0.63) ESR2ESR1MEN1KMT2AKDM4E
SCHEMBL25636436 0.81 ESR2 (0.43) ESR2ESR1MEN1KMT2AKDM4E
SCHEMBL23878247 0.80 ESR2 (0.60) ESR2ESR1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5219978-A Solvent soluble at ambient termperatures, high glass transition tempeatures and good thermo-oxidative stability HAY ALLAN S (CA) 1993-06-15 US claimed
US-5110993-A High glass transition temperature; thermo-oxidative stability HAY ALLAN S (CA) 1992-05-05 US claimed
EP-4585635-A1 POLYETHER NITRILE WITH IMPROVED CRYSTALLIZATION SPEED, METHOD FOR PRODUCING SAME, POLYETHER NITRILE RESIN COMPOSITION, AND METHOD FOR PRODUCING SAME Honshu Chemical Industry Co., Ltd. (JP) 2025-07-16 EP disclosed
US-20250026886-A1 METHOD FOR PRODUCING POLYETHER NITRILE HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2025-01-23 US disclosed
US-20250019342-A1 METHOD FOR PRODUCING POLYETHER NITRILE HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2025-01-16 US disclosed
US-20250011540-A1 METHOD FOR PRODUCING POLYETHER NITRILE HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2025-01-09 US disclosed
EP-4435033-A1 PRODUCTION METHOD OF POLYETHER NITRILE Honshu Chemical Industry Co., Ltd. (JP) 2024-09-25 EP disclosed
EP-4435035-A1 METHOD FOR PRODUCING POLYETHER NITRILE Honshu Chemical Industry Co., Ltd. (JP) 2024-09-25 EP disclosed
EP-4435034-A1 METHOD FOR PRODUCING POLYETHERNITRILE Honshu Chemical Industry Co., Ltd. (JP) 2024-09-25 EP disclosed
WO-2024117246-A1 POLYARYL ETHER KETONE, POLYARYL ETHER KETONE RESIN COMPOSITION, MOLDED ARTICLE OF SAID POLYARYL ETHER KETONE OR POLYARYL ETHER KETONE RESIN COMPOSITION, AND ELECTRONIC INSTRUMENT/DEVICE USING SAID POLYARYL ETHER KETONE OR POLYARYL ETHER KETONE RESIN COMPOSITION 本州化学工業株式会社 2024-06-06 WO disclosed
WO-2024053304-A1 POLYETHER NITRILE WITH IMPROVED CRYSTALLIZATION SPEED, METHOD FOR PRODUCING SAME, POLYETHER NITRILE RESIN COMPOSITION, AND METHOD FOR PRODUCING SAME 本州化学工業株式会社 2024-03-14 WO disclosed
EP-1479714-A1 Membrane-electrode assembly for direct methanol type fuel cell and proton conductive membrane JSR Corporation (JP) 2004-11-24 EP disclosed
US-6051294-A RETORT-STERILIZABLE PACKAGING MATERIALS EXHIBITING HIGH BARRIER TO OXYGEN THE DOW CHEMICAL COMPANY (US) 2000-04-18 US disclosed
US-5814373-A PACKAGING OF OXYGEN SENSITIVE MATERIALS INSIDE A CONTAINER COMPRISING A THERMOPLASTIC POLYMER DOW CHEMICAL COMPANY (US) 1998-09-29 US disclosed
US-5219978-A Solvent soluble at ambient termperatures, high glass transition tempeatures and good thermo-oxidative stability HAY ALLAN S (CA) 1993-06-15 US disclosed
US-5219978-A Solvent soluble at ambient termperatures, high glass transition tempeatures and good thermo-oxidative stability HAY ALLAN S (CA) 1993-06-15 US disclosed
US-5219978-A Solvent soluble at ambient termperatures, high glass transition tempeatures and good thermo-oxidative stability HAY ALLAN S (CA) 1993-06-15 US disclosed
US-5110993-A High glass transition temperature; thermo-oxidative stability HAY ALLAN S (CA) 1992-05-05 US disclosed
US-5110993-A High glass transition temperature; thermo-oxidative stability HAY ALLAN S (CA) 1992-05-05 US disclosed
US-5110993-A High glass transition temperature; thermo-oxidative stability HAY ALLAN S (CA) 1992-05-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250019342-A1 METHOD FOR PRODUCING POLYETHER NITRILE PAH, DBH, NISCH ESR2 1502/4885ESR1 804/4885MEN1 1418/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.