Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.74 |
| ▸ | MEN1 | O00255 | 6/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.74 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.67 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29684523 | 1.00 | KMT2A (0.74) | KMT2AMEN1SMN1; SMN2MAPTKCNK3 | |
| SCHEMBL23011772 | 0.89 | KCNK3 (0.82) | KMT2AMEN1SMN1; SMN2MAPTKCNK3 | |
| SCHEMBL10069478 | 0.81 | KMT2A (0.67) | KMT2AMEN1SMN1; SMN2MAPTKCNK3 | |
| SCHEMBL13874759 | 0.81 | MAPT (1.00) | KMT2AMEN1SMN1; SMN2MAPTKCNK3 | |
| SCHEMBL2529744 | 0.81 | LMNA (0.69) | KMT2AMEN1SMN1; SMN2MAPTKCNK3 | |
| SCHEMBL12496157 | 0.81 | KCNK3 (0.82) | KMT2AMEN1SMN1; SMN2MAPTKCNK3 | |
| SCHEMBL25351544 | 0.81 | SMN1; SMN2 (0.68) | KMT2AMEN1SMN1; SMN2MAPTKCNK3 | |
| SCHEMBL30535354 | 0.81 | SMN1; SMN2 (0.68) | KMT2AMEN1SMN1; SMN2MAPTKCNK3 | |
| SCHEMBL29684351 | 0.80 | KCNK3 (0.74) | KMT2AMEN1SMN1; SMN2MAPTKCNK3 | |
| SCHEMBL11077480 | 0.80 | KCNK3 (0.78) | KMT2AMEN1SMN1; SMN2MAPTKCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114763347-A | Compound for inducing mesenchymal stem cells to differentiate towards cartilage and application thereof | 华东师范大学 | 2022-07-19 | — | — | CN | claimed |
| CN-114763347-B | Compound for inducing mesenchymal stem cells to differentiate into cartilage and application thereof | 华东师范大学 | 2024-06-21 | — | — | CN | disclosed |
| CN-114763347-A | Compound for inducing mesenchymal stem cells to differentiate towards cartilage and application thereof | 华东师范大学 | 2022-07-19 | — | — | CN | disclosed |
| CN-114763346-A | Compound for inducing chondrogenesis and application thereof | 华东师范大学 | 2022-07-19 | — | — | CN | disclosed |