Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.62 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.58 |
| ▸ | F2 | P00734 | 2/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4887738 | 0.98 | KDM4E (0.64) | KDM4ECYP19A1NPC1RAB9ALMNA | |
| SCHEMBL27944084 | 0.93 | KDM4E (0.58) | KDM4ECYP19A1NPC1RAB9ALMNA | |
| SCHEMBL27954033 | 0.88 | LMNA (0.55) | KDM4ECYP19A1NPC1RAB9ALMNA | |
| SCHEMBL30869753 | 0.87 | CYP1A1 (0.68) | KDM4ECYP19A1NPC1RAB9ALMNA | |
| SCHEMBL31404848 | 0.84 | NPC1 (0.63) | KDM4ECYP19A1NPC1RAB9ALMNA | |
| SCHEMBL3711446 | 0.84 | NPC1 (0.63) | KDM4ECYP19A1NPC1RAB9ALMNA | |
| SCHEMBL10831846 | 0.81 | CYP1A1 (0.61) | KDM4ECYP19A1NPC1RAB9ALMNA | |
| SCHEMBL29047385 | 0.81 | CYP1A1 (0.60) | KDM4ECYP19A1NPC1RAB9ALMNA | |
| SCHEMBL12124985 | 0.80 | NPC1 (0.75) | KDM4ECYP19A1NPC1RAB9ALMNA | |
| SCHEMBL28809806 | 0.79 | NPC1 (0.58) | KDM4ECYP19A1NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110272370-B | Synthesis method of trifluoromethyl substituted 3,3' -bis (2-phenylindolyl) methane compound | 福州大学 | 2022-08-23 | — | — | CN | disclosed |