SCHEMBL28844941

SCHEMBL28844941

COCCOc1ccc(Cl)cc1NC(=O)c1cccs1

nearest known ligand 0.60

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KCNMA1 Q12791 1/20 0.60
KMT2A Q03164 4/20 0.60
ALDH1A1 P00352 4/20 0.60
MEN1 O00255 3/20 0.60
MAPT P10636 3/20 0.60
GAA P10253 3/20 0.60
L3MBTL1 Q9Y468 1/20 0.55
POLB P06746 2/20 0.54
KDM4E B2RXH2 4/20 0.53
IRAK4 Q9NWZ3 1/20 0.53
THRB P10828 2/20 0.53
APLNR P35414 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
LMNA P02545 2/20 0.50
HTT P42858 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29732897 1.00 KCNMA1 (0.60) KCNMA1KMT2AALDH1A1MEN1MAPT
SCHEMBL29684099 0.94 KCNMA1 (0.59) KCNMA1KMT2AALDH1A1MEN1MAPT
SCHEMBL29684333 0.91 KCNMA1 (0.60) KCNMA1KMT2AALDH1A1MEN1MAPT
SCHEMBL29684219 0.91 KDM4E (0.59) KCNMA1KMT2AALDH1A1MEN1MAPT
SCHEMBL29684588 0.90 KCNMA1 (0.57) KCNMA1KMT2AALDH1A1MEN1MAPT
SCHEMBL29684339 0.90 KCNMA1 (0.59) KCNMA1KMT2AALDH1A1MEN1MAPT
SCHEMBL29684399 0.89 KCNMA1 (0.62) KCNMA1KMT2AALDH1A1MEN1MAPT
SCHEMBL29684465 0.89 KCNMA1 (0.58) KCNMA1KMT2AALDH1A1MEN1MAPT
SCHEMBL29684685 0.88 KDM4E (0.64) KCNMA1KMT2AALDH1A1MEN1MAPT
SCHEMBL29684401 0.88 KCNMA1 (0.57) KCNMA1KMT2AALDH1A1MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114763347-A Compound for inducing mesenchymal stem cells to differentiate towards cartilage and application thereof 华东师范大学 2022-07-19 CN claimed
CN-114763347-B Compound for inducing mesenchymal stem cells to differentiate into cartilage and application thereof 华东师范大学 2024-06-21 CN disclosed
CN-114763347-A Compound for inducing mesenchymal stem cells to differentiate towards cartilage and application thereof 华东师范大学 2022-07-19 CN disclosed