Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13712986 | 0.78 | LPAR1 (0.52) | KDM4ESMN1; SMN2LMNATSHRL3MBTL1 | |
| SCHEMBL28147711 | 0.78 | CYP2C19 (0.38) | KDM4EALDH1A1SMN1; SMN2HSD17B10MAPT | |
| SCHEMBL28148698 | 0.78 | CYP2C19 (0.38) | KDM4EALDH1A1SMN1; SMN2HSD17B10MAPT | |
| SCHEMBL28724266 | 0.76 | KDM4E (0.43) | KDM4EALDH1A1SMN1; SMN2HSD17B10MAPT | |
| SCHEMBL1554320 | 0.75 | KDM4E (0.53) | KDM4EALDH1A1SMN1; SMN2HSD17B10MAPT | |
| SCHEMBL28370251 | 0.74 | KMT2A (0.43) | KDM4EALDH1A1MAPTTSHRL3MBTL1 | |
| SCHEMBL28088513 | 0.72 | CYSLTR2 (0.39) | — | |
| SCHEMBL11274523 | 0.72 | L3MBTL1 (0.50) | KDM4EALDH1A1SMN1; SMN2HSD17B10MAPT | |
| SCHEMBL4309048 | 0.72 | KDM4E (0.48) | KDM4EALDH1A1SMN1; SMN2HSD17B10MAPT | |
| SCHEMBL27556343 | 0.72 | KDM4E (0.40) | KDM4EMAPTLMNATSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106986832-A | Vegfr3 inhibitor | 癌症治疗合作研究中心有限公司 | 2017-07-28 | — | — | CN | disclosed |