Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIPK2 | Q9H2X6 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28148820 | 0.78 | PDE3B (0.40) | HIPK2LMNACYP3A4MAPTMAPK1 | |
| SCHEMBL29733493 | 0.76 | NR4A2 (0.46) | HIPK2LMNACYP3A4MAPTMAPK1 | |
| SCHEMBL1258573 | 0.76 | NR4A2 (0.46) | HIPK2LMNACYP3A4MAPTMAPK1 | |
| SCHEMBL26928523 | 0.74 | ALDH1A1 (0.44) | HIPK2LMNACYP3A4MAPTMAPK1 | |
| SCHEMBL30738206 | 0.73 | MAPT (0.43) | HIPK2LMNACYP3A4MAPTMAPK1 | |
| SCHEMBL1204569 | 0.73 | MAPT (0.43) | HIPK2LMNACYP3A4MAPTMAPK1 | |
| SCHEMBL1536295 | 0.73 | PLAU (0.51) | HIPK2LMNACYP3A4MAPTMAPK1 | |
| SCHEMBL3068849 | 0.73 | CYP3A4 (0.43) | HIPK2LMNACYP3A4MAPTMAPK1 | |
| SCHEMBL30111349 | 0.73 | PLAU (0.51) | HIPK2LMNACYP3A4MAPTMAPK1 | |
| SCHEMBL241172 | 0.73 | CYP3A4 (0.43) | HIPK2LMNACYP3A4MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105017152-B | Preparation method of 3-chloro-6-nitroisoquinoline or 3-bromine-6-nitroisoquinoline | 北京六合宁远科技有限公司 | 2017-05-10 | — | — | CN | disclosed |