Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.47 |
| ▸ | SCN4A | P35499 | 1/20 | 0.46 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Proline SCHEMBL1824937 | 0.95 | SCN4A (0.50) | SLC6A3SLC6A2SLC6A4SCN4ATSHR | |
| Proline SCHEMBL1824936 | 0.95 | SCN4A (0.50) | SLC6A3SLC6A2SLC6A4SCN4ATSHR | |
| Pipecolic Acid SCHEMBL27839677 | 0.82 | BLM (0.42) | TSHRCYP2D6ALDH1A1LMNA | |
| Pipecolic Acid SCHEMBL4758702 | 0.82 | BLM (0.45) | TSHRCYP2D6ALDH1A1LMNA | |
| Pipecolic Acid SCHEMBL1002076 | 0.82 | BLM (0.45) | TSHRCYP2D6ALDH1A1LMNA | |
| Pipecolic Acid SCHEMBL30552181 | 0.82 | — | — | |
| Pipecolic Acid SCHEMBL58642 | 0.82 | — | — | |
| Pipecolic Acid SCHEMBL1078450 | 0.82 | BLM (0.45) | TSHRCYP2D6ALDH1A1LMNA | |
| Pipecolic Acid SCHEMBL40185 | 0.82 | — | — | |
| Pipecolic Acid SCHEMBL22016 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115057810-A | Preparation method of ropivacaine hydrochloride intermediate | 山东科源制药股份有限公司 | 2022-09-16 | — | — | CN | claimed |
| CN-115057810-A | Preparation method of ropivacaine hydrochloride intermediate | 山东科源制药股份有限公司 | 2022-09-16 | — | — | CN | disclosed |