SCHEMBL28845136

SCHEMBL28845136

CCCCOC(=O)c1ccc(OCC(=O)OCC)cc1O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.62
CA12 O43570 1/20 0.54
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
CA7 P43166 1/20 0.54
CA9 Q16790 1/20 0.54
CA14 Q9ULX7 1/20 0.54
POLB P06746 1/20 0.52
PPARA Q07869 2/20 0.51
PPARG P37231 1/20 0.51
HSD17B10 Q99714 3/20 0.50
GAA P10253 3/20 0.50
MAPK1 P28482 3/20 0.50
TP53 P04637 2/20 0.50
KDM4E B2RXH2 2/20 0.50
LMNA P02545 2/20 0.50
ALDH1A1 P00352 2/20 0.50
GLA P06280 1/20 0.50
MAPT P10636 1/20 0.50
MEN1 O00255 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28845137 0.86 PPARA (0.50) HPGDPPARAPPARGHSD17B10GAA
SCHEMBL7472541 0.85 HPGD (0.67) HPGDCA12CA1CA2CA7
SCHEMBL12732188 0.84 HPGD (0.80) HPGDCA12CA1CA2CA7
SCHEMBL27733999 0.83 CA12 (0.61) CA12CA1CA2CA7CA9
SCHEMBL2010997 0.82 HPGD (0.70) HPGDHSD17B10GAAMAPK1TP53
SCHEMBL31198163 0.81 L3MBTL1 (0.60) HPGDCA12CA1CA2CA7
SCHEMBL9617126 0.81 SERPINE1 (0.75) CA12CA1CA2CA7CA9
SCHEMBL27931212 0.80 MAOB (0.65) POLBHSD17B10MAPK1TP53LMNA
SCHEMBL15913430 0.80 CA12 (0.57) HPGDCA12CA1CA2CA7
SCHEMBL7509875 0.79 TSHR (0.58) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116730785-A Method for synthesizing ester compound by light promotion 河南大学 2023-09-12 CN disclosed
CN-114933512-A Method for synthesizing ester compound under photocatalysis condition 河南大学 2022-08-23 CN disclosed