Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.51 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.51 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.51 |
| ▸ | P2RY10 | O00398 | 5/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.38 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.38 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21764567 | 0.90 | LPAR3 (0.57) | LPAR3LPAR2LPAR1P2RY10CES2 | |
| Sulfuric Acid SCHEMBL9664506 | 0.87 | LPAR3 (0.62) | LPAR3LPAR2LPAR1P2RY10LPAR5 | |
| SCHEMBL21764803 | 0.85 | CYP3A4 (0.50) | LPAR3LPAR2LPAR1P2RY10GPR34 | |
| SCHEMBL27540332 | 0.83 | CYP3A4 (0.48) | LPAR3LPAR2LPAR1P2RY10GPR34 | |
| Phosphoric Acid Monododecyl Ester SCHEMBL27494134 | 0.80 | LPAR3 (0.81) | LPAR3LPAR2LPAR1LPAR5 | |
| Phosphoric Acid Monododecyl Ester SCHEMBL27464086 | 0.80 | LPAR3 (0.81) | LPAR3LPAR2LPAR1LPAR5 | |
| Sulfuric Acid SCHEMBL9755184 | 0.80 | LPAR3 (0.46) | LPAR3LPAR2LPAR1P2RY10GPR34 | |
| SCHEMBL10936981 | 0.79 | LPAR3 (0.72) | LPAR3LPAR2LPAR1P2RY10LPAR5 | |
| SCHEMBL2211521 | 0.79 | LPAR3 (0.72) | LPAR3LPAR2LPAR1P2RY10LPAR5 | |
| SCHEMBL27514051 | 0.79 | LPAR3 (0.72) | LPAR3LPAR2LPAR1P2RY10LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104744972-B | Modified Alumina gel and ceramic coating and preparation method thereof | 江苏考普乐新材料有限公司 | 2017-06-09 | — | — | CN | disclosed |