Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TPMT | P51580 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL837798 | 0.93 | ALDH1A1 (0.56) | ALDH1A1KDM4ETAS1R3TAS1R1TAS1R2 | |
| SCHEMBL11342868 | 0.84 | ALDH1A1 (0.47) | ALDH1A1KDM4ETAS1R3TAS1R1TAS1R2 | |
| 2,6-Dichloroisonicotinic Acid SCHEMBL28513386 | 0.82 | TPMT (0.48) | ALDH1A1KDM4ELMNATDP1TPMT | |
| SCHEMBL668838 | 0.82 | KDM4E (0.69) | ALDH1A1KDM4ELMNATDP1TPMT | |
| SCHEMBL931870 | 0.80 | ALDH1A1 (0.52) | ALDH1A1KDM4ETAS1R3TAS1R1TAS1R2 | |
| SCHEMBL5761347 | 0.80 | ALDH1A1 (0.52) | ALDH1A1KDM4ETAS1R3TAS1R1TAS1R2 | |
| SCHEMBL28845230 | 0.79 | ALDH1A1 (0.53) | ALDH1A1KDM4ETAS1R3TAS1R1TAS1R2 | |
| SCHEMBL13570729 | 0.78 | ALDH1A1 (0.50) | ALDH1A1KDM4ETAS1R3TAS1R1TAS1R2 | |
| SCHEMBL31287794 | 0.78 | ALDH1A1 (0.76) | ALDH1A1KDM4ETAS1R3TAS1R1TAS1R2 | |
| SCHEMBL567975 | 0.78 | ALDH1A1 (0.76) | ALDH1A1KDM4ETAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115066438-A | ASGPR binding compounds for degrading extracellular proteins | 阿维拉治疗公司 | 2022-09-16 | — | — | CN | disclosed |