Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 6/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31680308 | 0.84 | ALDH1A1 (0.34) | TSHROPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL17610576 | 0.78 | TACR1 (0.42) | TACR1TSHROPRM1MEN1KMT2A | |
| SCHEMBL714091 | 0.74 | TSHR (0.48) | TACR1TSHRLTA4HMEN1KMT2A | |
| SCHEMBL10728607 | 0.74 | TSHR (0.35) | TSHROPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL27973569 | 0.73 | ALDH1A1 (0.38) | TSHROPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL28773272 | 0.73 | TMEM97 (0.38) | TACR1TSHROPRM1 | |
| SCHEMBL29112123 | 0.73 | TACR1 (0.43) | TACR1TSHROPRM1LTA4HMEN1 | |
| SCHEMBL11355291 | 0.73 | TACR1 (0.43) | TACR1TSHRLTA4HMEN1KMT2A | |
| SCHEMBL21082398 | 0.73 | TACR1 (0.43) | TACR1TSHRLTA4HMEN1KMT2A | |
| SCHEMBL28176655 | 0.73 | TACR1 (0.43) | TACR1TSHRLTA4HMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115066438-A | ASGPR binding compounds for degrading extracellular proteins | 阿维拉治疗公司 | 2022-09-16 | — | — | CN | disclosed |