Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | CCR1 | P32246 | 3/20 | 0.59 |
| ▸ | CCR5 | P51681 | 3/20 | 0.59 |
| ▸ | CCR8 | P51685 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
| ▸ | GMNN | O75496 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | MMP2 | P08253 | 1/20 | 0.59 |
| ▸ | MMP9 | P14780 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | MMP8 | P22894 | 1/20 | 0.59 |
| ▸ | THPO | P40225 | 1/20 | 0.59 |
| ▸ | MTOR | P42345 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30449837 | 0.98 | LMNA (0.61) | LMNACCR1CCR5CCR8KDM4E | |
| SCHEMBL1395123 | 0.98 | LMNA (0.61) | LMNACCR1CCR5CCR8KDM4E | |
| SCHEMBL30837267 | 0.96 | LMNA (0.59) | LMNACCR1CCR5CCR8KDM4E | |
| SCHEMBL29192757 | 0.96 | LMNA (0.59) | LMNACCR1CCR5CCR8KDM4E | |
| SCHEMBL28370016 | 0.91 | CCR1 (0.53) | LMNACCR1CCR5CCR8KDM4E | |
| SCHEMBL599374 | 0.90 | LMNA (0.67) | LMNACCR1CCR5CCR8KDM4E | |
| SCHEMBL23608092 | 0.90 | LMNA (0.52) | LMNACCR1CCR5CCR8KDM4E | |
| SCHEMBL30931575 | 0.90 | LMNA (0.52) | LMNACCR1CCR5CCR8KDM4E | |
| SCHEMBL20726792 | 0.90 | MAPT (0.52) | LMNACCR1CCR5CCR8KDM4E | |
| SCHEMBL23600052 | 0.90 | MAPT (0.52) | LMNACCR1CCR5CCR8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106749411-B | A kind of o-phenanthroline tetradentate ligands and the preparation method and application thereof | 浙江工业大学 | 2019-01-08 | — | — | CN | disclosed |
| CN-106749411-A | A kind of o-phenanthroline tetradentate ligandses and preparation method and application | 浙江工业大学 | 2017-05-31 | — | — | CN | disclosed |