Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAK | O14976 | 3/20 | 0.57 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.49 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.49 |
| ▸ | EPHA8 | P29322 | 1/20 | 0.49 |
| ▸ | TXK | P42681 | 1/20 | 0.49 |
| ▸ | COQ8A | Q8NI60 | 1/20 | 0.49 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.49 |
| ▸ | DNMT1 | P26358 | 3/20 | 0.49 |
| ▸ | DNMT3A | Q9Y6K1 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28845648 | 0.90 | NPSR1 (0.56) | GAKRIPK2EPHB6ABL1LCK | |
| Hydrochloric Acid SCHEMBL11735917 | 0.87 | GAK (0.56) | GAKRIPK2EPHB6ABL1LCK | |
| SCHEMBL10664310 | 0.85 | GAK (0.57) | GAKRIPK2EPHB6ABL1LCK | |
| SCHEMBL28845677 | 0.85 | GAK (0.54) | GAKRIPK2EPHB6ABL1LCK | |
| SCHEMBL29822705 | 0.84 | GAK (0.56) | GAKRIPK2EPHB6ABL1LCK | |
| Hydrochloric Acid SCHEMBL11523664 | 0.84 | GAK (0.56) | GAKRIPK2EPHB6ABL1LCK | |
| SCHEMBL11737693 | 0.83 | GAK (0.55) | GAKRIPK2EPHB6ABL1LCK | |
| Hydrochloric Acid SCHEMBL11738528 | 0.83 | GAK (0.55) | GAKRIPK2EPHB6ABL1LCK | |
| Hydrochloric Acid SCHEMBL10625573 | 0.83 | GAK (0.55) | GAKRIPK2EPHB6ABL1LCK | |
| SCHEMBL28845671 | 0.83 | GAK (0.53) | GAKRIPK2EPHB6ABL1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114773267-A | [ (7-trifluoromethyl quinoline-4-yl) amino ] benzamide compound and preparation and application thereof | 沈阳药科大学 | 2022-07-22 | — | — | CN | claimed |
| CN-114773267-B | [ (7-trifluoromethyl quinoline-4-yl) amino ] benzamide compound and preparation and application thereof | 沈阳药科大学 | 2024-01-26 | — | — | CN | disclosed |
| CN-114773267-A | [ (7-trifluoromethyl quinoline-4-yl) amino ] benzamide compound and preparation and application thereof | 沈阳药科大学 | 2022-07-22 | — | — | CN | disclosed |