Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13233508 | 0.94 | CETP (0.53) | CETPNR1I2 | |
| SCHEMBL13233510 | 0.89 | CETP (0.47) | CETPNR1I2 | |
| SCHEMBL2880060 | 0.89 | CETP (0.48) | CETPNR1I2 | |
| SCHEMBL2882016 | 0.87 | CETP (0.48) | CETPNR1I2 | |
| SCHEMBL2881497 | 0.87 | CETP (0.48) | CETPNR1I2 | |
| SCHEMBL4169245 | 0.87 | CETP (0.60) | CETPNR1I2 | |
| SCHEMBL4176575 | 0.85 | CETP (0.47) | CETP | |
| SCHEMBL14540347 | 0.85 | CETP (0.46) | CETPNR1I2 | |
| SCHEMBL2881413 | 0.85 | CETP (0.61) | CETPNR1I2 | |
| SCHEMBL13697573 | 0.85 | CETP (0.50) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100167986-A1 | Cholesteryl Ester Transfer Protein Inhibitors | MERCK SHARP & DOHME CORP. | 2010-07-01 | — | — | US | disclosed |
| US-20100167986-A1 | Cholesteryl Ester Transfer Protein Inhibitors | MERCK SHARP & DOHME CORP. | 2010-07-01 | — | — | US | disclosed |
| US-20100167986-A1 | Cholesteryl Ester Transfer Protein Inhibitors | MERCK SHARP & DOHME CORP. | 2010-07-01 | — | — | US | disclosed |
| EP-1942904-A2 | CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS | Merck & Co., Inc. (US) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007041494-A2 | CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS | MERCK & CO., INC. (US) | 2007-04-12 | — | — | WO | disclosed |
| WO-2007041494-A2 | CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS | MERCK & CO., INC. (US) | 2007-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100167986-A1 | Cholesteryl Ester Transfer Protein Inhibitors | CETP, LCAT, APOB | CETP 1/4885NR1I2 125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.