Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.56 |
| ▸ | PPARG | P37231 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 2/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.41 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.41 |
| ▸ | BCL9 | O00512 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28845986 | 1.00 | PPARA (0.56) | PPARAPPARGALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL28845978 | 0.91 | ALDH1A1 (0.49) | PPARAPPARGALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL15761572 | 0.91 | ALDH1A1 (0.49) | PPARAPPARGALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL28845980 | 0.89 | SMN1; SMN2 (0.49) | PPARAPPARGALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL29935359 | 0.89 | SMN1; SMN2 (0.49) | PPARAPPARGALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL15625932 | 0.87 | PPARG (0.52) | PPARAPPARGALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL27770773 | 0.84 | PPARA (0.58) | PPARAPPARGALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL12396358 | 0.83 | MAPT (0.53) | PPARAPPARGALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL2158928 | 0.83 | MAPT (0.53) | PPARAPPARGALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL28744809 | 0.82 | PPARG (0.52) | PPARAPPARGALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115073442-A | Disulfide bond-containing compound, preparation method thereof, pharmaceutical composition and application | 中国医学科学院药物研究所 | 2022-09-20 | — | — | CN | disclosed |