Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9485267 | 0.87 | LMNA (0.64) | LMNASMN1; SMN2MEN1KMT2AMAPK1 | |
| Albendazole SCHEMBL7969988 | 0.85 | LMNA (0.83) | LMNASMN1; SMN2MEN1KMT2AMAPK1 | |
| Albendazole SCHEMBL29409236 | 0.85 | LMNA (0.83) | LMNASMN1; SMN2MEN1KMT2AMAPK1 | |
| Albendazole SCHEMBL44682 | 0.85 | LMNA (0.83) | LMNASMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL23894242 | 0.84 | LMNA (0.60) | LMNASMN1; SMN2MEN1KMT2AMAPK1 | |
| Albendazole SCHEMBL28582887 | 0.84 | LMNA (0.81) | LMNASMN1; SMN2MEN1KMT2AMAPK1 | |
| Albendazole SCHEMBL28958723 | 0.84 | LMNA (0.81) | LMNASMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL7258031 | 0.83 | LMNA (0.69) | LMNASMN1; SMN2MEN1KMT2AMAPK1 | |
| Albendazole SCHEMBL23038783 | 0.82 | LMNA (0.74) | LMNASMN1; SMN2MEN1KMT2AMAPK1 | |
| Albendazole SCHEMBL23038781 | 0.82 | LMNA (0.74) | LMNASMN1; SMN2MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115073380-A | 2-amide substituted benzo five-membered nitrogen-containing heterocyclic compound and preparation method and application thereof | 青海大学 | 2022-09-20 | — | — | CN | disclosed |