Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25177265 | 1.00 | SMN1; SMN2 (0.34) | SMN1; SMN2HTTCHRNB2CHRNA5CHRNA7 | |
| SCHEMBL29470610 | 1.00 | SMN1; SMN2 (0.34) | SMN1; SMN2HTTCHRNB2CHRNA5CHRNA7 | |
| Hydrochloric Acid SCHEMBL28737239 | 0.98 | SMN1; SMN2 (0.36) | SMN1; SMN2HTTCHRNB2CHRNA5CHRNA7 | |
| SCHEMBL28634630 | 0.95 | SMN1; SMN2 (0.30) | SMN1; SMN2 | |
| SCHEMBL28643389 | 0.79 | — | — | |
| SCHEMBL3905171 | 0.77 | SMN1; SMN2 (0.38) | SMN1; SMN2HTTCHRNB2CHRNA5CHRNA7 | |
| SCHEMBL688825 | 0.77 | SMN1; SMN2 (0.38) | SMN1; SMN2HTTCHRNB2CHRNA5CHRNA7 | |
| SCHEMBL688697 | 0.77 | SMN1; SMN2 (0.38) | SMN1; SMN2HTTCHRNB2CHRNA5CHRNA7 | |
| SCHEMBL29022706 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL21801417 | 0.76 | SMN1; SMN2 (0.40) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115073344-B | Preparation method and application of R- (1-tert-butyloxycarbonyl pyrrolidine-2-yl) acrylic acid | 苏州富士莱医药股份有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-115073344-A | Preparation method and application of R- (1-tert-butyloxycarbonyl-pyrrolidine-2-yl) acrylic acid | 苏州富士莱医药股份有限公司 | 2022-09-20 | — | — | CN | claimed |
| CN-115073344-B | Preparation method and application of R- (1-tert-butyloxycarbonyl pyrrolidine-2-yl) acrylic acid | 苏州富士莱医药股份有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-115073344-B | Preparation method and application of R- (1-tert-butyloxycarbonyl pyrrolidine-2-yl) acrylic acid | 苏州富士莱医药股份有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-115073344-A | Preparation method and application of R- (1-tert-butyloxycarbonyl-pyrrolidine-2-yl) acrylic acid | 苏州富士莱医药股份有限公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-115073344-A | Preparation method and application of R- (1-tert-butyloxycarbonyl-pyrrolidine-2-yl) acrylic acid | 苏州富士莱医药股份有限公司 | 2022-09-20 | — | — | CN | disclosed |
| WO-2022053000-A1 | CARBOCYCLIC AMIDE DERIVATIVE AND APPLICATION THEREOF IN MEDICINE | 四川海思科制药有限公司 | 2022-03-17 | — | — | WO | disclosed |