⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL245689 | 0.97 | — | — | |
| Methylamine SCHEMBL27328071 | 0.95 | GRIN2D (0.48) | — | |
| Hydrochloric Acid SCHEMBL394301 | 0.95 | — | — | |
| Bromide SCHEMBL14862173 | 0.95 | — | — | |
| SCHEMBL27649824 | 0.90 | MEN1 (0.52) | — | |
| SCHEMBL30712 | 0.90 | — | — | |
| SCHEMBL27759094 | 0.89 | GRIN2D (0.44) | — | |
| Acetamide SCHEMBL27620721 | 0.89 | EPHX1 (0.48) | — | |
| SCHEMBL28042030 | 0.89 | GRIN2D (0.44) | — | |
| Iodide SCHEMBL5155254 | 0.88 | MEN1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115504909-A | Benzoylguanidine derivative and preparation method and application thereof | 青岛海洋生物医药研究院 | 2022-12-23 | — | — | CN | claimed |
| WO-2022237798-A1 | BENZOYLGUANIDINE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 青岛海洋生物医药研究院 | 2022-11-17 | — | — | WO | claimed |
| CN-115317474-A | Application of benzoylguanidine derivative in preparation of medicine for preventing and treating nervous system diseases or cardiovascular system diseases | 中国海洋大学 | 2022-11-11 | — | — | CN | claimed |
| CN-115073329-B | Novel leonurine derivative and preparation method and application thereof | 中国海洋大学 | 2024-01-26 | — | — | CN | disclosed |
| CN-115504909-A | Benzoylguanidine derivative and preparation method and application thereof | 青岛海洋生物医药研究院 | 2022-12-23 | — | — | CN | disclosed |
| WO-2022237798-A1 | BENZOYLGUANIDINE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 青岛海洋生物医药研究院 | 2022-11-17 | — | — | WO | disclosed |
| CN-115317474-A | Application of benzoylguanidine derivative in preparation of medicine for preventing and treating nervous system diseases or cardiovascular system diseases | 中国海洋大学 | 2022-11-11 | — | — | CN | disclosed |
| CN-115073329-A | Novel leonurine derivative and preparation method and application thereof | 中国海洋大学 | 2022-09-20 | — | — | CN | disclosed |
| CN-115068462-A | Application of novel leonurine marine derivative in preparation of medicines for preventing and treating inflammatory diseases or allergy | 中国海洋大学 | 2022-09-20 | — | — | CN | disclosed |