Hydrochloric Acid

Hydrochloric Acid

SCHEMBL394301

CCCCNC(=N)N.Cl

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL245689 0.97
Methylamine SCHEMBL27328071 0.95 GRIN2D (0.48)
Ammonia Solution, Strong SCHEMBL28846277 0.95
Bromide SCHEMBL14862173 0.95
Hydrochloric Acid SCHEMBL5477741 0.91 SPHK1 (0.54)
Hydrochloric Acid SCHEMBL4168689 0.91 SPHK1 (0.54)
Dodine SCHEMBL425946 0.91 SPHK1 (0.54)
Hydrochloric Acid SCHEMBL5319578 0.91 SPHK1 (0.54)
Hydrochloric Acid SCHEMBL14862037 0.91 SPHK1 (0.54)
Hydrochloric Acid SCHEMBL1738411 0.91 SPHK1 (0.54)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105693972-B The preparation method of antibacterial modified polyurethane flexible foam 华东理工大学 2019-06-14 CN claimed
CN-116723714-A Modified perovskite film, efficient stable perovskite solar cell and preparation method thereof 华侨大学 2023-09-08 CN disclosed
CN-116723714-A Modified perovskite film, efficient stable perovskite solar cell and preparation method thereof 华侨大学 2023-09-08 CN disclosed
CN-111154370-B Antibacterial acrylate coating and preparation method and application thereof 华东理工大学 2021-06-08 CN disclosed
WO-2020218835-A1 NOVEL POLYIMIDE-TYPE POLYMER AND PREPARATION METHOD THEREFOR 서울대학교 산학협력단 2020-10-29 WO disclosed
CN-111154370-A Antibacterial acrylate coating and preparation method and application thereof 华东理工大学 2020-05-15 CN disclosed
CN-105693972-B The preparation method of antibacterial modified polyurethane flexible foam 华东理工大学 2019-06-14 CN disclosed
CN-107690281-A Cystic fibrosis transmembrane transduction modulator modulators 弗特克斯药品有限公司 2018-02-13 CN disclosed
CN-104822670-A 5-phenoxy-3h-pyrimidin-4-one derivatives and their use as HIV reverse transcriptase inhibitors MERCK SHARP & DOHME 2015-08-05 CN disclosed
EP-1983051-B1 Isolation and purification of nucleic acid molecules with solid phase ROCHE DIAGNOSTICS GMBH (DE) 2014-11-26 EP disclosed
EP-2035401-B1 ARYL- AND HETEROARYL-ETHYL-ACYLGUANIDINE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS SANOFI AVENTIS (FR) 2011-02-23 EP disclosed
US-20090203696-A1 Aryl- and Heteroaryl-Ethyl-Acylguanidine Derivatives, Their Preparation and Their Application in Therapeutics SANOFI-AVENTIS (FR) 2009-08-13 US disclosed
EP-2035401-A2 ARYL- AND HETEROARYL-ETHYL-ACYLGUANIDINE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS Sanofi-Aventis (FR) 2009-03-18 EP disclosed
US-20080319182-A1 ISOLATION AND PURIFICATION OF NUCLEIC ACIDS WITH A SOLID PHASE ROCHE DIAGNOSTICS GMBH (DE) 2008-12-25 US disclosed
EP-1983051-A2 Isolation and purification of nucleic acid molecules with solid phase Roche Diagnostics GmbH (DE) 2008-10-22 EP disclosed
EP-1449519-B1 Liquid composition containing a guanidine amide group derivative and/or a salt thereof AJINOMOTO KK (JP) 2008-07-09 EP disclosed
EP-1873200-A1 An improved process for making an external plasticization of aliphatic polyamides and plasticizers useful for said plasticization Arkema France (FR) 2008-01-02 EP disclosed
WO-2007144769-A2 ARYL- AND HETEROARYL-ETHYL-ACYLGUANIDINE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS SANOFI-AVENTIS (FR) 2007-12-21 WO disclosed
US-20040176464-A1 Liquid composition with improved storage stability, which contains an amide group-containing guanidine derivative or/and a salt thereof AJINOMOTO CO., INC. (JP) 2004-09-09 US disclosed
EP-1449519-A1 Liquid composition containing a guanidine amide group derivative and/or a salt thereof Ajinomoto Co., Inc. (JP) 2004-08-25 EP disclosed