Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 10/20 | 0.55 |
| ▸ | LPAR2 | Q9HBW0 | 7/20 | 0.55 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CDC25A | P30304 | 1/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.42 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7804477 | 0.94 | LPAR3 (0.56) | LPAR3LPAR2LPAR1CYP3A4AKT1 | |
| SCHEMBL27453510 | 0.91 | CYP3A4 (0.56) | LPAR3LPAR2LPAR1CYP3A4 | |
| SCHEMBL30631114 | 0.90 | LPAR3 (0.53) | LPAR3LPAR2LPAR1CYP3A4AKT1 | |
| SCHEMBL2184531 | 0.87 | LPAR3 (0.59) | LPAR3LPAR2LPAR1CYP3A4AKT1 | |
| SCHEMBL7540607 | 0.87 | LPAR3 (0.59) | LPAR3LPAR2LPAR1CYP3A4AKT1 | |
| SCHEMBL9257620 | 0.87 | LPAR3 (0.59) | LPAR3LPAR2LPAR1CYP3A4AKT1 | |
| SCHEMBL11671731 | 0.87 | LPAR3 (0.59) | LPAR3LPAR2LPAR1CYP3A4AKT1 | |
| SCHEMBL5033156 | 0.87 | LPAR3 (0.48) | LPAR3LPAR2LPAR1CYP3A4FAAH | |
| SCHEMBL11671572 | 0.87 | LPAR3 (0.59) | LPAR3LPAR2LPAR1CYP3A4AKT1 | |
| SCHEMBL3815174 | 0.87 | LPAR3 (0.59) | LPAR3LPAR2LPAR1CYP3A4AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114945652-A | Friction modifier compounds and related compositions and methods | 雅富顿化学公司 | 2022-08-26 | — | — | CN | claimed |
| CN-114945652-A | Friction modifier compounds and related compositions and methods | 雅富顿化学公司 | 2022-08-26 | — | — | CN | disclosed |