SCHEMBL9257620

SCHEMBL9257620

CCCCCCCCOP(=O)(CCCC)OCCCCCCCC

nearest known ligand 0.59

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 10/20 0.59
LPAR2 Q9HBW0 7/20 0.59
LPAR1 Q92633 3/20 0.59
CYP3A4 P08684 1/20 0.50
AKT1 P31749 2/20 0.47
LMNA P02545 1/20 0.47
ESR1 P03372 1/20 0.47
ADORA3 P0DMS8 1/20 0.47
CDC25A P30304 1/20 0.47
AGTR1 P30556 1/20 0.47
ADRA1A P35348 1/20 0.47
KCNH2 Q12809 1/20 0.47
TERT O14746 1/20 0.42
UCHL3 P15374 1/20 0.42
MAPK14 Q16539 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5583932 1.00 LPAR3 (0.59) LPAR3LPAR2LPAR1CYP3A4AKT1
SCHEMBL10496294 1.00 LPAR3 (0.59) LPAR3LPAR2LPAR1CYP3A4AKT1
SCHEMBL11668838 1.00 LPAR3 (0.59) LPAR3LPAR2LPAR1CYP3A4AKT1
SCHEMBL7106488 1.00 LPAR3 (0.59) LPAR3LPAR2LPAR1CYP3A4AKT1
SCHEMBL23650045 0.98 LPAR3 (0.57) LPAR3LPAR2LPAR1CYP3A4AKT1
SCHEMBL1296681 0.98 LPAR3 (0.57) LPAR3LPAR2LPAR1CYP3A4AKT1
SCHEMBL11878700 0.98 LPAR3 (0.57) LPAR3LPAR2LPAR1CYP3A4AKT1
SCHEMBL1296828 0.98 LPAR3 (0.57) LPAR3LPAR2LPAR1CYP3A4AKT1
SCHEMBL731433 0.98 LPAR3 (0.57) LPAR3LPAR2LPAR1CYP3A4AKT1
SCHEMBL9262129 0.98 LPAR3 (0.57) LPAR3LPAR2LPAR1CYP3A4AKT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5439606-A Automatic transmission fluids; preblending a phosdphorus ester and a alkenyl succinimide or succinamide; heating in presence of water to hydrolyze ester ETHYL PETROLEUM ADDITIVES, INC. (US) 1995-08-08 US disclosed
US-5389273-A An automatic transmission fluid mixture comprising a base oils , viscosity index promoters, a phosphorus-containing polyisobutylene succinimide or succinamide; wear resistance, high viscosity ETHYL PETROLEUM ADDITIVES, INC. (US) 1995-02-14 US disclosed
US-5256324-A Using phosphorus ester and boron compound; wear resistant automatic transmission fluid ETHYL PETROLEUM ADDITIVES, INC. (US) 1993-10-26 US disclosed
US-5198133-A Modified succinimide or sucinamide dispersants and their production ETHYL PETROLEUM ADDITIVES, INC. (US) 1993-03-30 US disclosed
EP-0384639-B1 PRECONDITIONED AUTOMATIC TRANSMISSION FLUIDS AND THEIR PREPARATION ETHYL PETROLEUM ADDITIVES, INC. (US) 1993-03-17 EP disclosed
US-5164103-A Automatic transmission fluid, antiwear ETHYL PETROLEUM ADDITIVES, INC. (US) 1992-11-17 US disclosed
EP-0333371-B1 HOMOGENEOUS ADDITIVE CONCENTRATES AND THEIR FORMATION ETHYL PETROLEUM ADDITIVES, INC. (US) 1991-10-23 EP disclosed
EP-0384639-A1 Preconditioned automatic transmission fluids and their preparation ETHYL PETROLEUM ADDITIVES, INC. (US) 1990-08-29 EP disclosed
EP-0333371-A1 Homogeneous additive concentrates and their formation ETHYL PETROLEUM ADDITIVES, INC. (US) 1989-09-20 EP disclosed
US-4855074-A Homogeneous additive concentrates and their formation ETHYL PETROLEUM ADDITIVES, INC. (US) 1989-08-08 US disclosed
US-4242479-A CATALYST OF ALUMINUM TRIHALIDE, ORGANOSILOXANE COMPOUND OR ETHER, MAGNESIUM ALCOHOLATE, TITANIUM-HALOGEN AND ORGANOALUMINUM COMPOUNDS SHOWA YUKA KABUSHIKI KAISHA (JP) 1980-12-30 US disclosed
US-4180636-A MAGNESIUM HALIDE, TITANIUM COMPOUND ELECTRON DONOR COMPOUND, TRIALKYL ALUMINUM CATALYST SHOWA DENKO KABUSHIKI KAISHA (JP) 1979-12-25 US disclosed