Chloroform

Chloroform

SCHEMBL28846288

CC(C)(C)CC(O)(C(=O)O)c1cccc(C(C)(C)C)c1.ClC(Cl)Cl

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.41
RXRA P19793 3/20 0.40
RXRB P28702 3/20 0.40
NR1H4 Q96RI1 1/20 0.39
CYP2C19 P33261 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP26A1 O43174 2/20 0.38
CYP26B1 Q9NR63 2/20 0.38
HDAC8 Q9BY41 2/20 0.38
HDAC4 P56524 1/20 0.38
HDAC2 Q92769 1/20 0.38
RXRG P48443 1/20 0.37
CTSL P07711 1/20 0.36
KCNJ6 P48051 1/20 0.36
KCNJ5 P48544 1/20 0.36
KCNJ3 P48549 1/20 0.36
NOTUM Q6P988 1/20 0.35
NR4A1 P22736 1/20 0.35
NR4A2 P43354 1/20 0.35
NR4A3 Q92570 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25294724 0.94 ACHE (0.45) ACHERXRARXRBNR1H4CYP2C19
Methane SCHEMBL27773188 0.92 ACHE (0.44) ACHERXRARXRBNR1H4CYP2C19
SCHEMBL28207893 0.92 ACHE (0.44) ACHERXRARXRBNR1H4CYP2C19
Hydrazine SCHEMBL27719623 0.91 ACHE (0.43) ACHERXRARXRBNR1H4CYP2C19
Cetostearyl Alcohol SCHEMBL28141858 0.81 SCN5A (0.43) ACHERXRARXRBHDAC8HDAC4
SCHEMBL27266174 0.81 CYP2C19 (0.48) CYP2C19CYP1A2HDAC8HDAC4HDAC2
SCHEMBL27710745 0.80 SCN5A (0.45) ACHERXRARXRBNR1H4CYP2C19
SCHEMBL28133333 0.80 ACHE (0.46) ACHERXRARXRBNR1H4CYP2C19
SCHEMBL28524311 0.79 ACHE (0.43) ACHERXRARXRBNR1H4CYP26A1
SCHEMBL27616257 0.77 ACHE (0.41) ACHERXRARXRBNR1H4CYP26A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106751389-A A kind of engineering plastics for LDS technologies of light color and preparation method thereof 上海中镭新材料科技有限公司 2017-05-31 CN disclosed