Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.75 |
| ▸ | MAPT | P10636 | 10/20 | 0.67 |
| ▸ | MEN1 | O00255 | 6/20 | 0.67 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28846346 | 1.00 | KMT2A (0.75) | KMT2AMAPTMEN1HCAR3KDM4E | |
| SCHEMBL20798382 | 0.90 | HCAR3 (0.74) | KMT2AMAPTMEN1HCAR3KDM4E | |
| SCHEMBL20798381 | 0.90 | HCAR3 (0.74) | KMT2AMAPTMEN1HCAR3KDM4E | |
| SCHEMBL19858272 | 0.82 | HCAR3 (0.52) | KMT2AMAPTMEN1HCAR3KDM4E | |
| SCHEMBL30921528 | 0.82 | KMT2A (0.71) | KMT2AMAPTMEN1HCAR3KDM4E | |
| SCHEMBL29262732 | 0.82 | KMT2A (0.71) | KMT2AMAPTMEN1HCAR3KDM4E | |
| SCHEMBL4966338 | 0.82 | HCAR3 (0.54) | KMT2AMAPTMEN1HCAR3KDM4E | |
| SCHEMBL4966333 | 0.82 | HCAR3 (0.54) | KMT2AMAPTMEN1HCAR3KDM4E | |
| SCHEMBL1810940 | 0.81 | MAPT (0.66) | KMT2AMAPTMEN1HCAR3ALDH1A1 | |
| SCHEMBL16037933 | 0.81 | MAPT (0.66) | KMT2AMAPTMEN1HCAR3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114073703-B | Compositions and methods for treating nonalcoholic steatohepatitis | 苏州亚盛药业有限公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-114073703-A | Compositions and methods for treating nonalcoholic steatohepatitis | 苏州亚盛药业有限公司 | 2022-02-22 | — | — | CN | disclosed |