Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4843010 | 0.82 | SHBG (0.39) | DPP4DPP7LMNAEPHX1CYP2C9 | |
| SCHEMBL21245994 | 0.82 | SHBG (0.39) | DPP4DPP7LMNAEPHX1CYP2C9 | |
| SCHEMBL24920003 | 0.82 | SHBG (0.39) | DPP4DPP7LMNAEPHX1CYP2C9 | |
| SCHEMBL936012 | 0.80 | — | — | |
| SCHEMBL13494936 | 0.78 | TP53 (0.59) | DPP4DPP7TP53LMNAKDM4E | |
| SCHEMBL4843531 | 0.78 | SHBG (0.41) | DPP4DPP7TP53LMNAEPHX1 | |
| SCHEMBL5339146 | 0.77 | DPP4 (0.36) | DPP4DPP7 | |
| SCHEMBL14588833 | 0.76 | DPP4 (0.43) | DPP4DPP7LMNACYP2C9 | |
| SCHEMBL24126295 | 0.76 | DPP4 (0.43) | DPP4DPP7LMNACYP2C9 | |
| SCHEMBL20696926 | 0.76 | DPP4 (0.43) | DPP4DPP7LMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107207476-A | Indoles and 7-azaindole derivatives and its for the purposes in neurodegenerative disorders | 默克专利有限公司 | 2017-09-26 | — | — | CN | disclosed |