Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 20/20 | 0.62 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.50 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.50 |
| ▸ | AR | P10275 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2880165 | 0.99 | PGR (0.61) | PGRNR3C1NR3C2AR | |
| SCHEMBL14989874 | 0.81 | PGR (0.65) | PGRNR3C1NR3C2AR | |
| SCHEMBL17471460 | 0.81 | PGR (0.71) | PGRNR3C1NR3C2AR | |
| SCHEMBL6777233 | 0.81 | PGR (0.61) | PGRNR3C1NR3C2AR | |
| SCHEMBL3990671 | 0.81 | PGR (0.69) | PGRNR3C1NR3C2AR | |
| SCHEMBL4809621 | 0.77 | PGR (1.00) | PGRNR3C1NR3C2AR | |
| SCHEMBL13579113 | 0.75 | PGR (0.77) | PGRNR3C1NR3C2AR | |
| SCHEMBL5505137 | 0.75 | PGR (0.91) | PGRNR3C1NR3C2AR | |
| SCHEMBL2885095 | 0.75 | PGR (0.63) | PGRAR | |
| SCHEMBL5436855 | 0.74 | PGR (1.00) | PGRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100234422-A1 | Sulfonylated Heterocycles Useful for Modulation of the Progesterone Receptor | WYETH LLC (US) | 2010-09-16 | — | — | US | disclosed |
| US-7750038-B2 | Sulfonylated heterocycles useful for modulation of the progesterone receptor | WYETH LLC (US) | 2010-07-06 | — | — | US | disclosed |
| EP-2121657-A1 | SULFONYLATED HETEROCYCLES USEFUL FOR MODULATION OF THE PROGESTERONE RECEPTOR | Wyeth (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008109056-A1 | SULFONYLATED HETEROCYCLES USEFUL FOR MODULATION OF THE PROGESTERONE RECEPTOR | WYETH (US) | 2008-09-12 | — | — | WO | disclosed |
| US-20080221160-A1 | SULFONYLATED HETEROCYCLES USEFUL FOR MODULATION OF THE PROGESTERONE RECEPTOR | WYETH (US) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221160-A1 | SULFONYLATED HETEROCYCLES USEFUL FOR MODULATION OF THE PROGESTERONE RECEPTOR | GNRHR, FSHR, PRLHR | PGR 5/4885NR3C1 521/4885NR3C2 220/4885 |
| US-20100234422-A1 | Sulfonylated Heterocycles Useful for Modulation of the Progesterone Receptor | GNRHR, FSHR, PRLHR | PGR 5/4885NR3C1 521/4885NR3C2 220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.