D-Glutamate

D-Glutamate

SCHEMBL28847437

C[C@](N)(CCC(=O)O)C(=O)O.NC(CCC(=O)O)C(=O)O

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.62
GRM8 O00222 2/20 0.62
GRM6 O15303 2/20 0.62
GRM7 Q14831 2/20 0.62
GRM4 Q14833 2/20 0.62
GRIN2D O15399 1/20 0.62
GRIN3B O60391 1/20 0.62
GSR P00390 1/20 0.62
GRIK1 P39086 1/20 0.62
GRM5 P41594 1/20 0.62
GRIA1 P42261 1/20 0.62
GRIA2 P42262 1/20 0.62
GRIA3 P42263 1/20 0.62
SLC1A3 P43003 1/20 0.62
SLC1A2 P43004 1/20 0.62
SLC1A1 P43005 1/20 0.62
GRIA4 P48058 1/20 0.62
GRIN1 Q05586 1/20 0.62
GRIN2A Q12879 1/20 0.62
GRIK2 Q13002 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL473835 0.83 ALDH1A1 (0.56) CYP1A2KMT2AALOX15BLMPMP22
SCHEMBL200536 0.83 ALDH1A1 (0.56) CYP1A2KMT2AALOX15BLMPMP22
SCHEMBL200537 0.83 ALDH1A1 (0.56) CYP1A2KMT2AALOX15BLMPMP22
Water SCHEMBL10780977 0.81 ALDH1A1 (0.54) CYP1A2GRM2KMT2AALOX15BLM
Water SCHEMBL10780975 0.81 ALDH1A1 (0.54) CYP1A2GRM2KMT2AALOX15BLM
Water SCHEMBL434488 0.81 ALDH1A1 (0.54) CYP1A2GRM2KMT2AALOX15BLM
D-Glutamate SCHEMBL27849133 0.81 GRM8 (0.86) CYP1A2GRM8GRM6GRM7GRM4
D-Glutamate SCHEMBL27627916 0.80 GRM8 (0.75) CYP1A2GRM8GRM6GRM7GRM4
Glutamic Acid SCHEMBL27740036 0.80 GRM8 (0.75) CYP1A2GRM8GRM6GRM7GRM4
D-Glutamate SCHEMBL9449715 0.79 GRM8 (0.90) CYP1A2GRM8GRM6GRM7GRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115087352-A Carbon dioxide generation 勒芬天主教大学 2022-09-20 CN disclosed