Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28847430 | 0.83 | ALDH1A1 (0.41) | TSHRMAPTMEN1KMT2ALMNA | |
| SCHEMBL13375299 | 0.82 | TSHR (0.47) | TSHRMAPTMEN1KMT2APOLB | |
| SCHEMBL2554501 | 0.82 | TSHR (0.50) | TSHRMAPTMEN1KMT2APOLB | |
| SCHEMBL17506789 | 0.80 | MEN1 (0.44) | TSHRMAPTMEN1KMT2ALMNA | |
| SCHEMBL28847477 | 0.79 | ALDH1A1 (0.43) | TSHRMAPTALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL29580615 | 0.79 | PDGFRB (0.51) | TSHRMAPTMEN1KMT2ALMNA | |
| SCHEMBL364995 | 0.78 | SMN1; SMN2 (0.46) | MAPTL3MBTL1LMNAALDH1A1CYP3A4 | |
| SCHEMBL29902938 | 0.78 | MEN1 (0.43) | TSHRMAPTMEN1KMT2APOLB | |
| SCHEMBL13375073 | 0.78 | TSHR (0.46) | TSHRMAPTMEN1KMT2APOLB | |
| SCHEMBL11219818 | 0.75 | TSHR (0.59) | TSHRMAPTMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4077316-A1 | BENZIMIDAZOLE DERIVATIVES | Pfizer Inc. (US) | 2022-10-26 | — | — | EP | disclosed |
| CN-115087655-A | Benzimidazole derivatives | 辉瑞公司 | 2022-09-20 | — | — | CN | disclosed |