Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.66 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8904885 | 0.84 | UBE2T (0.61) | UBE2TASIC3SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL3117628 | 0.83 | UBE2T (0.66) | UBE2TASIC3SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL19372016 | 0.83 | UBE2T (0.70) | UBE2TASIC3SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL226465 | 0.83 | UBE2T (0.70) | UBE2TASIC3SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL2047532 | 0.81 | SMN1; SMN2 (0.62) | UBE2TASIC3SMN1; SMN2RAB9ANPC1 | |
| Bromide SCHEMBL7601035 | 0.81 | UBE2T (0.68) | UBE2TASIC3SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL5537342 | 0.80 | SMN1; SMN2 (0.60) | UBE2TASIC3SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL16397518 | 0.79 | UBE2T (0.66) | UBE2TASIC3SMN1; SMN2RAB9ANPC1 | |
| Fluoride SCHEMBL7600822 | 0.79 | UBE2T (0.66) | UBE2TASIC3SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL322456 | 0.79 | UBE2T (0.66) | UBE2TASIC3SMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091929-A1 | AGENTS THAT DISRUPT CELLULAR REPLICATION AND THEIR USE IN INHIBITING PATHOLOGICAL CONDITIONS | The European Molecular Biology Laboratory (DE) | 2009-08-26 | — | — | EP | claimed |
| CN-101421257-A | Agents that disrupt cellular replication and their use in inhibiting pathological conditions | EUROPEAN MOLECULAR BIOLOGY LAB EMBL (DE) | 2009-04-29 | — | — | CN | claimed |
| WO-2007107352-A1 | AGENTS THAT DISRUPT CELLULAR REPLICATION AND THEIR USE IN INHIBITING PATHOLOGICAL CONDITIONS | THE EUROPEAN MOLECULAR BIOLOGY LABORATORY (DE) | 2007-09-27 | — | — | WO | claimed |
| CN-1061213-C | Combating fish parasites | BAYER AG (DE) | 2001-01-31 | — | — | CN | claimed |
| US-5504081-A | ADMINISTERING NICOTINERGIC ACETYLCHOLINE RECEPTOR ANTAGONISTS AND AGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-02 | — | — | US | claimed |
| US-4692529-A | Method for synthesizing a magenta coupler by selectively etherifying 4-hydroxy-5-pyrazolone | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1987-09-08 | — | — | US | claimed |
| EP-4261830-A1 | NOVEL PEPTIDOMIMETIC COMPOUND AND DESIGN | Oita University Institute of Advanced Medicine, Inc. (JP) | 2023-10-18 | — | — | EP | disclosed |
| CN-116615423-A | Novel peptidomimetic compounds and design | 株式会社大分大学先端医学研究所 | 2023-08-18 | — | — | CN | disclosed |
| US-11661410-B2 | Tricyclic compounds as histone methyltransferase inhibitors | GLOBAL BLOOD THERAPEUTICS, INC. (US) | 2023-05-30 | — | — | US | disclosed |
| US-11584734-B2 | Tricyclic compounds as histone methyltransferase inhibitors | GLOBAL BLOOD THERAPEUTICS, INC. (US) | 2023-02-21 | — | — | US | disclosed |
| US-20230002351-A1 | TRICYCLIC COMPOUNDS AS HISTONE METHYLTRANSFERASE INHIBITORS | GLOBAL BLOOD THERAPEUTICS, INC. | 2023-01-05 | — | — | US | disclosed |
| US-20200361896-A1 | TRICYCLIC COMPOUNDS AS HISTONE METHYLTRANSFERASE INHIBITORS | GLOBAL BLOOD THERAPEUTICS, INC. | 2020-11-19 | — | — | US | disclosed |
| CN-111372927-A | Tricyclic compounds as histone methyltransferase inhibitors | 全球血液疗法股份有限公司 | 2020-07-03 | — | — | CN | disclosed |
| EP-0368946-A4 | 1,2-DIOXETANES. | QUEST SYSTEMS INC (US) | 1990-05-14 | — | — | EP | disclosed |
| WO-1989006226-A1 | SYNTHESIS OF 1,2-DIOXETANES AND INTERMEDIATES THEREFOR | QUEST SYSTEMS, INC. (US) | 1989-07-13 | — | — | WO | disclosed |
| CN-88101027-A | Growth promoting composition and preparation method thereof | — | 1988-08-31 | — | — | CN | disclosed |
| US-4692529-A | Method for synthesizing a magenta coupler by selectively etherifying 4-hydroxy-5-pyrazolone | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1987-09-08 | — | — | US | disclosed |
| EP-0215355-A2 | Erythromycin derivative and process for preparing the same | KITASATO KENKYUSHO (JP) | 1987-03-25 | — | — | EP | disclosed |
| EP-0213617-A2 | Digestive tract contractile motion stimulant | KITASATO KENKYUSHO (JP) | 1987-03-11 | — | — | EP | disclosed |
| US-4399075-A | Process for producing chlorinated phenoxytoluene derivatives | ASAHI CHEMICAL COMPANY, LIMITED (JP) | 1983-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002351-A1 | TRICYCLIC COMPOUNDS AS HISTONE METHYLTRANSFERASE INHIBITORS | EHMT1, EHMT2, BMI1 | UBE2T 989/4885ASIC3 4294/4885SMN1; SMN2 400/4885 |
| US-11661410-B2 | Tricyclic compounds as histone methyltransferase inhibitors | EHMT1, EHMT2, BMI1 | UBE2T 989/4885ASIC3 4294/4885SMN1; SMN2 400/4885 |
| US-11584734-B2 | Tricyclic compounds as histone methyltransferase inhibitors | EHMT1, EHMT2, BMI1 | UBE2T 1382/4885ASIC3 4189/4885SMN1; SMN2 349/4885 |
| US-20200361896-A1 | TRICYCLIC COMPOUNDS AS HISTONE METHYLTRANSFERASE INHIBITORS | EHMT1, EHMT2, BMI1 | UBE2T 1382/4885ASIC3 4189/4885SMN1; SMN2 349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.