Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27695977 | 0.78 | NPC1 (0.37) | HPGDKDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL10499420 | 0.74 | NR4A1 (0.55) | HPGDKDM4EL3MBTL1KMT2APOLB | |
| SCHEMBL29277471 | 0.74 | LMNA (0.47) | KDM4EL3MBTL1KMT2APOLBGAA | |
| SCHEMBL22880595 | 0.73 | CDC25B (0.40) | HPGDKDM4EL3MBTL1KMT2APOLB | |
| Hydrazine SCHEMBL28964205 | 0.73 | NR4A1 (0.59) | HPGDKDM4EL3MBTL1KMT2APOLB | |
| SCHEMBL4404102 | 0.73 | NR4A1 (0.59) | HPGDKDM4EL3MBTL1KMT2APOLB | |
| SCHEMBL27824177 | 0.73 | LMNA (0.45) | HPGDKDM4EKMT2APOLBGAA | |
| SCHEMBL5987790 | 0.73 | NR4A1 (0.63) | HPGDKDM4EL3MBTL1KMT2APOLB | |
| SCHEMBL29459734 | 0.73 | NR4A1 (0.63) | HPGDKDM4EL3MBTL1KMT2APOLB | |
| SCHEMBL29990575 | 0.73 | NR4A1 (0.63) | HPGDKDM4EL3MBTL1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108631-A | It is used as the deazapurine derivatives of 6 amino, 7 two ring 7 of kinases inhibitor | 内尔维阿诺医学科学有限公司 | 2017-08-29 | — | — | CN | disclosed |