Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | CASP7 | P55210 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.39 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1161258 | 0.77 | TAAR1 (1.00) | TAAR1ALDH1A1HSD17B10MAPTKDM4E | |
| SCHEMBL21295866 | 0.77 | KDM4E (0.36) | TAAR1ALDH1A1HSD17B10GAAMAPT | |
| SCHEMBL28879160 | 0.76 | KDM4E (0.49) | TAAR1ALDH1A1HSD17B10GAAMAPT | |
| SCHEMBL29755699 | 0.75 | KDM4E (0.51) | TAAR1ALDH1A1HSD17B10GAAMAPT | |
| SCHEMBL7116127 | 0.75 | KDM4E (0.51) | TAAR1ALDH1A1HSD17B10GAAMAPT | |
| SCHEMBL9246341 | 0.73 | HSD17B10 (0.63) | TAAR1ALDH1A1HSD17B10MAPTKDM4E | |
| SCHEMBL29007097 | 0.73 | MAPT (0.53) | TAAR1ALDH1A1HSD17B10GAAMAPT | |
| SCHEMBL2008325 | 0.73 | TAAR1 (0.45) | TAAR1ALDH1A1HSD17B10GAAMAPT | |
| SCHEMBL15695597 | 0.72 | TAAR1 (0.55) | TAAR1ALDH1A1HSD17B10GAAMAPT | |
| SCHEMBL13941274 | 0.71 | HSD17B10 (0.60) | TAAR1ALDH1A1HSD17B10MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107669669-A | novel glucagon receptor antagonist | 症变治疗公司 | 2018-02-09 | — | — | CN | disclosed |
| CN-101610995-B | Glucagon receptor antagonists | 症变治疗公司 | 2017-08-08 | — | — | CN | disclosed |