Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | BLM | P54132 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | CASP1 | P29466 | 2/20 | 0.49 |
| ▸ | CASP7 | P55210 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.49 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.49 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29755699 | 0.96 | KDM4E (0.51) | KDM4EALDH1A1HSD17B10HPGDMEN1 | |
| SCHEMBL7116127 | 0.96 | KDM4E (0.51) | KDM4EALDH1A1HSD17B10HPGDMEN1 | |
| SCHEMBL29007097 | 0.84 | MAPT (0.53) | KDM4EALDH1A1HSD17B10HPGDMEN1 | |
| SCHEMBL7404185 | 0.82 | TAAR1 (0.64) | KDM4EALDH1A1HSD17B10HPGDMEN1 | |
| SCHEMBL28879182 | 0.80 | ABL1 (0.61) | KDM4EALDH1A1HSD17B10HPGDMEN1 | |
| SCHEMBL24689433 | 0.78 | PIK3R1 (0.46) | KDM4EALDH1A1HSD17B10HPGDMEN1 | |
| SCHEMBL28583448 | 0.77 | GSTP1 (0.53) | KDM4EALDH1A1HSD17B10HPGDMEN1 | |
| SCHEMBL162083 | 0.77 | TAAR1 (0.62) | KDM4EALDH1A1HSD17B10HPGDMEN1 | |
| Tannin Pyrogallol SCHEMBL13685561 | 0.76 | ALDH1A1 (0.64) | ALDH1A1HSD17B10HPGDMEN1BLM | |
| SCHEMBL5951150 | 0.76 | ALDH1A1 (0.64) | ALDH1A1HSD17B10HPGDMEN1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110143935-B | Preparation method of 2, 5-disubstituted furan derivative | 华侨大学 | 2022-09-30 | — | — | CN | disclosed |