Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 3/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28071638 | 0.89 | RXFP1 (0.56) | MRGPRX4RXFP1ABL1ABCG2NQO2 | |
| SCHEMBL27613559 | 0.83 | CYP1A2 (0.54) | KDM4EALDH1A1GABRA2GABRB2MAPT | |
| SCHEMBL9222973 | 0.82 | MAPK1 (0.46) | ABCG2NQO2KDM4EALDH1A1HTT | |
| SCHEMBL18572013 | 0.81 | CA12 (0.47) | ABCG2KDM4EALDH1A1HTTGABRA2 | |
| SCHEMBL28847805 | 0.80 | MAPT (0.49) | ABCG2PLA2G2AKDM4EALDH1A1HTT | |
| SCHEMBL3364680 | 0.80 | ABCG2 (0.56) | ABCG2KDM4EALDH1A1HTTMAPT | |
| SCHEMBL19478133 | 0.80 | DYRK1A (0.52) | PLA2G2ACNR2KDM4EALDH1A1MAPT | |
| SCHEMBL13534720 | 0.80 | ALDH1A1 (0.41) | ABCG2NQO2CNR2KDM4EALDH1A1 | |
| SCHEMBL3364585 | 0.80 | NQO2 (0.50) | ABCG2NQO2KDM4EALDH1A1HTT | |
| SCHEMBL4957637 | 0.80 | MAPT (0.44) | MRGPRX4PLA2G2ACNR2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110156680-B | Preparation method of 4- (dimethoxymethyl) quinoline-2-methyl formate derivative | 济南大学 | 2022-12-30 | — | — | CN | disclosed |
| CN-110156760-B | Preparation method of 4- (1, 4-dioxane-2-yl) quinoline-2-methyl formate derivative | 济南大学 | 2022-09-30 | — | — | CN | disclosed |