Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 17/20 | 0.71 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | F5 | P12259 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14991291 | 0.83 | EP300 (1.00) | EP300CREBBPMEN1KMT2ARAB9A | |
| SCHEMBL14991292 | 0.83 | EP300 (1.00) | EP300CREBBPMEN1KMT2ARAB9A | |
| SCHEMBL29711734 | 0.83 | EP300 (1.00) | EP300CREBBPMEN1KMT2ARAB9A | |
| SCHEMBL29441235 | 0.83 | EP300 (1.00) | EP300CREBBPMEN1KMT2ARAB9A | |
| SCHEMBL12092858 | 0.83 | EP300 (1.00) | EP300CREBBPMEN1KMT2ARAB9A | |
| SCHEMBL14990918 | 0.82 | EP300 (0.51) | EP300CREBBPMEN1KMT2AALDH1A1 | |
| SCHEMBL14990917 | 0.82 | EP300 (0.51) | EP300CREBBPMEN1KMT2AALDH1A1 | |
| SCHEMBL28883613 | 0.78 | EP300 (1.00) | EP300CREBBPMEN1KMT2ARAB9A | |
| SCHEMBL28362136 | 0.78 | EP300 (0.66) | EP300CREBBPMEN1KMT2AALDH1A1 | |
| SCHEMBL28362223 | 0.78 | EP300 (0.65) | EP300CREBBPMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115124517-B | Aromatic compound, preparation method, pharmaceutical composition and application thereof | 复旦大学 | 2024-06-18 | — | — | CN | disclosed |
| CN-115124517-A | Aromatic compound, preparation method thereof, pharmaceutical composition and application | 复旦大学 | 2022-09-30 | — | — | CN | disclosed |