⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29655399 | 1.00 | — | — | |
| SCHEMBL31713001 | 0.88 | — | — | |
| SCHEMBL31712968 | 0.86 | — | — | |
| SCHEMBL31712935 | 0.79 | — | — | |
| SCHEMBL30978396 | 0.77 | — | — | |
| SCHEMBL30786882 | 0.76 | — | — | |
| SCHEMBL31712928 | 0.72 | — | — | |
| SCHEMBL31712918 | 0.71 | — | — | |
| SCHEMBL7358073 | 0.71 | — | — | |
| SCHEMBL674111 | 0.68 | CYP11B1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230339882-A1 | SHP2 INHIBITOR AND COMPOSITION AND APPLICATION THEREOF | BETTA PHARMACEUTICALS CO., LTD. (CN) | 2023-10-26 | — | — | US | claimed |
| EP-4186896-A1 | SHP2 INHIBITOR AND COMPOSITION AND APPLICATION THEREOF | Betta Pharmaceuticals Co., Ltd (CN) | 2023-05-31 | — | — | EP | claimed |
| US-4272606-A | HYDRAZIDE, THIOAMIDE | FUJI PHOTO FILM CO., LTD. (JP) | 1981-06-09 | — | — | US | claimed |
| CN-116640095-A | Diaryl amine derivative containing aliphatic carboxyl and preparation method and application thereof | 山东大学 | 2023-08-25 | — | — | CN | disclosed |
| CN-111315747-B | Dihydropyrazolopyrimidine compound and preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-111315747-B | Dihydropyrazolopyrimidine compound and preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-05-02 | — | — | CN | disclosed |
| EP-4058457-A2 | NITROGEN OXIDE-DONATING PDE-5 AND/OR PDE-6 INHIBITOR COMPOUNDS | Ildong Pharmaceutical Co., Ltd. (KR) | 2022-09-21 | — | — | EP | disclosed |
| WO-2022096930-A2 | NITROGEN OXIDE-DONATING PDE-5 AND/OR PDE-6 INHIBITOR COMPOUNDS, AND USES THEREOF | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2022-05-12 | — | — | WO | disclosed |
| EP-3366688-B1 | SUBSTITUTED PYRAZOLOPYRIMIDINES AS GLUCOCEREBROSIDASE ACTIVATORS | US HEALTH (US) | 2022-02-09 | — | — | EP | disclosed |
| WO-2021094830-A2 | NITROGEN OXIDE-DONATING PDE-5 AND/OR PDE-6 INHIBITOR COMPOUNDS | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2021-05-20 | — | — | WO | disclosed |
| US-10925874-B2 | Substituted pyrazolopyrimidines as glucocerebrosidase activators | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2021-02-23 | — | — | US | disclosed |
| US-20030008020-A1 | Methods for remodeling neuronal and cardiovascular pathways | QUEEN'S UNIVERSITY OF KINGSTON (CA) | 2003-01-09 | — | — | US | disclosed |
| US-6458797-B1 | IN ILIO-HYPOGASTRIC-PUDENDAL ARTERIAL BED AND GENITALIA BY ADMINISTERING TO HUMANS THERAPEUTICALLY EFFECTIVE AMOUNT OF ANTI-PRESSOR AGENT | QUEEN'S UNIVERSITY OF KINGSTON (CA) | 2002-10-01 | — | — | US | disclosed |
| EP-1235563-A2 | USE OF ANTI(W)PRESSOR AGENTS FOR VASCULAR REMODELING IN GENITAL DYSFUNCTION | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2002-09-04 | — | — | EP | disclosed |
| US-20020035067-A1 | Methods for remodeling neuronal and cardiovascular pathways | CELLEGY PHARMACEUTICALS, INC. | 2002-03-21 | — | — | US | disclosed |
| US-6284763-B1 | ADMINISTERING LOW DOSAGE OF ANTIPRESSOR AGENT | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2001-09-04 | — | — | US | disclosed |
| WO-2000012110-A2 | USE OF ANTI(W)PRESSOR AGENTS FOR VASCULAR REMODELING IN GENITAL DYSFUNCTION | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2000-03-09 | — | — | WO | disclosed |
| US-5187042-A | Monodisperse emulsion containing hydrazine derivative and redox compound capable of releasing development inhibitor when oxidized; high contrast images | FUJI PHOTO FILM CO., LTD. (JP) | 1993-02-16 | — | — | US | disclosed |
| US-4914002-A | High contrast image, high sensitivity | FUJI PHOTO FILM CO., LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| US-4272606-A | HYDRAZIDE, THIOAMIDE | FUJI PHOTO FILM CO., LTD. (JP) | 1981-06-09 | — | — | US | disclosed |