Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | MB | P02144 | 1/20 | 0.37 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30978396 | 0.80 | — | — | |
| SCHEMBL15386171 | 0.73 | BCL6 (0.40) | CYP11B1CYP11B2PDE3BPDE3A | |
| SCHEMBL29246512 | 0.72 | NPC1 (0.37) | CYP11B1CYP11B2PDE3BPDE3A | |
| SCHEMBL31752325 | 0.72 | NPC1 (0.37) | CYP11B1CYP11B2PDE3BPDE3A | |
| SCHEMBL673377 | 0.72 | CYP11B1 (0.42) | CYP11B1CYP11B2MBBIRC2PDE3B | |
| SCHEMBL7419264 | 0.71 | BIRC2 (0.37) | CYP11B1CYP11B2MBBIRC2PDE3B | |
| SCHEMBL4791581 | 0.70 | MKNK2 (0.30) | MKNK2 | |
| SCHEMBL1270310 | 0.70 | MB (0.56) | CYP11B1CYP11B2MBPDE3BPDE3A | |
| SCHEMBL29547390 | 0.70 | MB (0.56) | CYP11B1CYP11B2MBPDE3BPDE3A | |
| SCHEMBL7358073 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117736210-A | Aromatic heterocyclic compound, and preparation method and application thereof | 上海翊石医药科技有限公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-114805341-B | Aromatic heterocyclic compound, and preparation method and application thereof | 上海翊石医药科技有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-114805341-A | Aromatic heterocyclic compounds and preparation method and application thereof | 上海翊石医药科技有限公司 | 2022-07-29 | — | — | CN | disclosed |
| US-20150190504-A1 | WOUND HEALING | KINETIC CONCEPTS, INC. | 2015-07-09 | — | — | US | disclosed |
| US-8957076-B2 | Wound healing | SYSTAGENIX WOUND MANAGEMENT (US), INC. (US) | 2015-02-17 | — | — | US | disclosed |
| US-8063052-B2 | Wound healing | SYSTAGENIX WOUND MANAGEMENT (US), INC. (US) | 2011-11-22 | — | — | US | disclosed |
| US-20100099622-A1 | WOUND HEALING | SYSTAGENIX WOUND MANAGEMENT (US), INC. (US) | 2010-04-22 | — | — | US | disclosed |
| US-20090170910-A1 | WOUND HEALING | KCI USA, INC. | 2009-07-02 | — | — | US | disclosed |
| EP-1786409-A1 | WOUND HEALING | ETHICON, INC. (US) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006028836-A1 | WOUND HEALING | ETHICON, INC. (US) | 2006-03-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099622-A1 | WOUND HEALING | MAPK1, MAPK3, MAPK4 | CYP11B1 2444/4885CYP11B2 2642/4885MB 2719/4885 |
| US-20090170910-A1 | WOUND HEALING | MAPK1, MAPK3, MAPK4 | CYP11B1 2444/4885CYP11B2 2642/4885MB 2719/4885 |
| US-20150190504-A1 | WOUND HEALING | MAPK1, MAPK3, MAPK4 | CYP11B1 2444/4885CYP11B2 2642/4885MB 2719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.