SCHEMBL28848546

SCHEMBL28848546

CC1(C)CC(=O)CC(C)(C)N1c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
GSK3A P49840 3/20 0.42
GSK3B P49841 3/20 0.42
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
RAB9A P51151 2/20 0.39
GAA P10253 1/20 0.39
NPC1 O15118 1/20 0.39
CYP11B2 P19099 1/20 0.38
ELANE P08246 2/20 0.38
CACNA1B Q00975 1/20 0.38
APBA1 Q02410 1/20 0.38
MAPK1 P28482 1/20 0.38
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL410238 0.74 GSK3A (0.37) ALDH1A1CYP1A2CYP2C9CYP2C19GSK3A
SCHEMBL28875627 0.72 GSK3A (0.35) ALDH1A1CYP1A2CYP2C9CYP2C19GSK3A
SCHEMBL28130991 0.72 GSK3A (0.35) ALDH1A1CYP1A2CYP2C9CYP2C19GSK3A
SCHEMBL11151939 0.72 MEN1 (0.51) ALDH1A1CYP1A2CYP2C19MEN1KMT2A
SCHEMBL10813336 0.71 ELANE (0.50) ALDH1A1GSK3AGSK3BMEN1KMT2A
SCHEMBL16694551 0.71 ALDH1A1 (0.38) ALDH1A1CYP1A2CYP2C9CYP2C19MEN1
SCHEMBL12758292 0.69 MAPT (0.49) ALDH1A1CYP2C9CYP2C19GAA
SCHEMBL12589187 0.69 ALDH1A1 (0.37) ALDH1A1CYP1A2CYP2C9CYP2C19MEN1
SCHEMBL28160128 0.69 MAOB (0.39) GSK3AGSK3BCACNA1BAPBA1
SCHEMBL9242285 0.67 ALDH1A1 (0.54) ALDH1A1MEN1KMT2AGAAELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107531724-A Method for preparing isosorbide ethoxylate dimethacrylate 巴斯夫欧洲公司 2018-01-02 CN disclosed
CN-107001296-A The method for preparing lotus hydroxyl ketone (methyl) acrylate 巴斯夫欧洲公司 2017-08-01 CN disclosed