Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28848556 | 1.00 | AHR (0.51) | AHRALOX5FNTAFNTBPTGS1 | |
| SCHEMBL30842466 | 0.81 | LMNA (0.39) | AHRALOX5FNTAFNTB | |
| SCHEMBL31037543 | 0.78 | PTGS1 (0.31) | ALOX5FNTAFNTBPTGS1PTGS2 | |
| SCHEMBL30040131 | 0.77 | LCK (0.52) | ALOX5PTGS1PTGS2CYP19A1 | |
| SCHEMBL28603095 | 0.74 | AHR (0.53) | AHRALOX5PTGS1PTGS2 | |
| SCHEMBL3813128 | 0.74 | AHR (0.61) | AHRALOX5PTGS1PTGS2 | |
| SCHEMBL3813125 | 0.74 | AHR (0.61) | AHRALOX5PTGS1PTGS2 | |
| SCHEMBL28603093 | 0.74 | AHR (0.53) | AHRALOX5PTGS1PTGS2 | |
| SCHEMBL20657984 | 0.73 | AHR (0.69) | AHRALOX5PTGS1PTGS2 | |
| SCHEMBL28580517 | 0.72 | AHR (0.69) | AHRALOX5PTGS1PTGS2ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114957171-A | Novel five-membered heterocyclic substituted styrene derivative and preparation method and application thereof | 广东工业大学 | 2022-08-30 | — | — | CN | disclosed |