Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 14/20 | 0.35 |
| ▸ | GRM5 | P41594 | 3/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20743016 | 0.78 | PDE10A (0.45) | MAP3K5PDE10A | |
| SCHEMBL28652012 | 0.77 | KDM4C (0.55) | — | |
| SCHEMBL28660342 | 0.76 | KDM4C (0.43) | MAP3K5PDE10A | |
| SCHEMBL25316841 | 0.76 | MAP3K5 (0.47) | MAP3K5NPC1RAB9ANLRP3 | |
| SCHEMBL21461042 | 0.76 | MAP3K5 (0.42) | MAP3K5 | |
| SCHEMBL30352583 | 0.76 | MAP3K5 (0.47) | MAP3K5NPC1RAB9ANLRP3 | |
| SCHEMBL28392385 | 0.74 | CYP2E1 (0.42) | — | |
| SCHEMBL25316032 | 0.74 | NPC1 (0.53) | MAP3K5NPC1RAB9ANLRP3 | |
| SCHEMBL28848718 | 0.74 | MAP3K5 (0.38) | MAP3K5GRM5NPC1RAB9A | |
| SCHEMBL25318462 | 0.74 | MAP3K5 (0.42) | MAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110036005-B | Amide derivatives and their use in medicine | 广东东阳光药业有限公司 | 2022-09-27 | — | — | CN | disclosed |